Gene Page: HMGCS2

Summary
GeneID  3158
Symbol  HMGCS2
Synonyms  -
Description  3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
See related  HGNC:5008|MIM:600234|Ensembl:ENSG00000134240|HPRD:02580|
Locus tag  -
Gene type  protein-coding
Map location  1p13-p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ANP32A0.950.90
HDAC20.940.90
RBMX0.940.90
SET0.940.91
HNRNPH10.940.90
RSL1D10.930.85
NONO0.930.91
TIGD10.930.85
UIMC10.930.88
HNRNPA30.920.91
Top 10 negatively co-expressed genes
HLA-F-0.67-0.79
C5orf53-0.66-0.73
FBXO2-0.66-0.67
AIFM3-0.65-0.73
TNFSF12-0.65-0.64
ALDOC-0.65-0.69
PTH1R-0.64-0.70
LDHD-0.64-0.66
CA4-0.63-0.77
LHPP-0.63-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004421hydroxymethylglutaryl-CoA synthase activityEXP11479731 
GO:0004421hydroxymethylglutaryl-CoA synthase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008152metabolic processIEA-
GO:0006695cholesterol biosynthetic processIEA-
GO:0008299isoprenoid biosynthetic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionTAS7851882 
GO:0005743mitochondrial inner membraneIEA-
GO:0005759mitochondrial matrixEXP11479731 
 


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