Gene Page: HPN

Summary
GeneID  3249
Symbol  HPN
Synonyms  TMPRSS1
Description  hepsin (transmembrane protease, serine 1)
See related  HGNC:5155|MIM:142440|Ensembl:ENSG00000105707|HPRD:00801|
Locus tag  -
Gene type  protein-coding
Map location  19q11-q13.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ETS20.860.84
SIRPA0.860.83
SV2B0.850.76
MAST30.850.76
TYRO30.850.76
MFSD40.840.77
LRRK10.840.83
RASGRF20.840.77
BMPER0.840.84
SUSD50.840.80
Top 10 negatively co-expressed genes
HEBP2-0.46-0.61
BCL7C-0.46-0.54
SH2D2A-0.42-0.44
TRAF4-0.41-0.45
KIAA1949-0.41-0.26
PDE9A-0.41-0.36
TUBB2B-0.41-0.35
RPS19P3-0.40-0.54
RPL35-0.40-0.48
RPL18-0.40-0.50
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0005044scavenger receptor activityIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA18029348 
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS1885621 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4961972041A,m8hsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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