Gene Page: HSPB2

Summary
GeneID  3316
Symbol  HSPB2
Synonyms  HSP27|Hs.78846|LOH11CR1K|MGC133245|MKBP
Description  heat shock 27kDa protein 2
See related  HGNC:5247|MIM:602179|Ensembl:ENSG00000170276|HPRD:03712|
Locus tag  -
Gene type  protein-coding
Map location  11q22-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATP5J0.830.79
C8orf590.810.73
CCDC720.800.74
NDUFA120.800.74
MRPL220.790.74
MRPL130.790.75
UBL50.780.75
COX160.770.71
COX7B0.770.71
ALG50.770.70
Top 10 negatively co-expressed genes
SLC6A6-0.54-0.52
MYH9-0.50-0.47
FMN2-0.48-0.46
SPTBN1-0.47-0.43
CSMD1-0.46-0.43
SH3PXD2A-0.46-0.44
TECPR2-0.45-0.44
MAGI2-0.45-0.42
C14orf43-0.45-0.45
BAT2D1-0.45-0.43
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14594798 
GO:0008047enzyme activator activityTAS9490724 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006986response to unfolded proteinNAS9344664 
GO:0007525somatic muscle developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolTAS9490724 
GO:0005625soluble fractionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CLK4DKFZp686A20267CDC-like kinase 4-HPRD12705895 
CRYABCRYA2 | CTPP2 | HSPB5crystallin, alpha BTwo-hybridBioGRID10625651 
DMPKDM | DM1 | DM1PK | DMK | MDPK | MT-PKdystrophia myotonica-protein kinase-HPRD,BioGRID9490724 
HSPB2HSP27 | Hs.78846 | LOH11CR1K | MGC133245 | MKBPheat shock 27kDa protein 2Affinity Capture-Western
Two-hybrid
BioGRID10625651 
HSPB3HSPL27heat shock 27kDa protein 3-HPRD,BioGRID10625651 
HSPB8CMT2L | DHMN2 | E2IG1 | H11 | HMN2 | HMN2A | HSP22heat shock 22kDa protein 8Affinity Capture-Western
Two-hybrid
BioGRID11342557 |14594798 
MAPKAPK5PRAKmitogen-activated protein kinase-activated protein kinase 5Biochemical ActivityBioGRID9628874 
UBL5FLJ46917 | HUB1 | MGC131795ubiquitin-like 5Two-hybridBioGRID12705895 
 


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