Gene Page: APOA4

Summary
GeneID  337
Symbol  APOA4
Synonyms  MGC142154|MGC142156
Description  apolipoprotein A-IV
See related  HGNC:602|MIM:107690|Ensembl:ENSG00000110244|HPRD:00130|
Locus tag  -
Gene type  protein-coding
Map location  11q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005507copper ion bindingIDA16945374 
GO:0005319lipid transporter activityTAS3080432 
GO:0008289lipid bindingIEA-
GO:0017127cholesterol transporter activityIDA1935934 
GO:0016209antioxidant activityIDA16945374 
GO:0042803protein homodimerization activityIDA1935934 
GO:0031210phosphatidylcholine bindingIDA1935934 |11940599 
GO:0043499eukaryotic cell surface bindingIDA1935934 
GO:0060228phosphatidylcholine-sterol O-acyltransferase activator activityIDA1935934 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002227innate immune response in mucosaIDA15254593 
GO:0008203cholesterol metabolic processIDA1935934 
GO:0006982response to lipid hydroperoxideIDA16945374 
GO:0006869lipid transportIEA-
GO:0007159leukocyte adhesionIDA15254593 
GO:0033344cholesterol effluxIDA1935934 |11162594 
GO:0042157lipoprotein metabolic processIEA-
GO:0042744hydrogen peroxide catabolic processIDA16945374 
GO:0019430removal of superoxide radicalsIDA16945374 
GO:0034445negative regulation of plasma lipoprotein oxidationIDA16945374 
GO:0032374regulation of cholesterol transportIDA11940599 
GO:0033700phospholipid effluxIDA11162594 
GO:0042632cholesterol homeostasisIDA1935934 
GO:0043691reverse cholesterol transportIDA3095477 
GO:0044240multicellular organismal lipid catabolic processIDA3095477 
GO:0046470phosphatidylcholine metabolic processIDA1935934 
GO:0055088lipid homeostasisIDA3095477 
GO:0065005protein-lipid complex assemblyIMP16159879 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005788endoplasmic reticulum lumenEXP12692552 
GO:0005576extracellular regionEXP4345202 |12692552 
GO:0005576extracellular regionNAS14718574 
GO:0005615extracellular spaceIDA1935934 
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0034364high-density lipoprotein particleIDA3095477 
GO:0034361very-low-density lipoprotein particleIDA3095477 
GO:0042627chylomicronIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GPLD1GPIPLD | GPIPLDM | MGC22590 | PIGPLD | PIGPLD1glycosylphosphatidylinositol specific phospholipase D1-HPRD,BioGRID11254757 
 


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