Gene Page: SHROOM2

Summary
GeneID  357
Symbol  SHROOM2
Synonyms  APXL|DKFZp781J074|FLJ39277|HSAPXL
Description  shroom family member 2
See related  HGNC:630|MIM:300103|Ensembl:ENSG00000146950|HPRD:02113|
Locus tag  -
Gene type  protein-coding
Map location  Xp22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
METTL7B0.770.21
CABP70.700.37
CHRNA10.690.45
WNK40.680.10
PROC0.680.33
FIBCD10.680.30
C2orf850.640.18
CNGB10.640.33
ADRA1A0.620.30
GABRQ0.620.28
Top 10 negatively co-expressed genes
FAM36A-0.17-0.29
CCAR1-0.16-0.23
RP9-0.15-0.17
OLFM2-0.15-0.21
EIF5B-0.15-0.26
LYAR-0.15-0.19
NKIRAS2-0.15-0.11
SH2B2-0.15-0.27
RANBP17-0.15-0.13
ZNF193-0.15-0.15
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008013beta-catenin bindingISS16684770 
GO:0051015actin filament bindingISS16684770 
GO:0015280amiloride-sensitive sodium channel activityTAS7795590 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentISSBrain (GO term level: 7)-
GO:0000902cell morphogenesisISS16684770 
GO:0002089lens morphogenesis in camera-type eyeISS-
GO:0008057eye pigment granule organizationISS-
GO:0007275multicellular organismal developmentIEA-
GO:0043482cellular pigment accumulationISS-
GO:0016477cell migrationISS-
GO:0051017actin filament bundle formationISS16684770 
GO:0032438melanosome organizationISS-
GO:0032401establishment of melanosome localizationISS-
GO:0045176apical protein localizationISS-
GO:0043583ear developmentISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005923tight junctionISSBrain (GO term level: 10)-
GO:0005856cytoskeletonISS-
GO:0005874microtubuleIEA-
GO:0005737cytoplasmIEA-
GO:0005913cell-cell adherens junctionISS16684770 
GO:0005886plasma membraneISS-
GO:0016324apical plasma membraneISS16684770 
GO:0030054cell junctionIEA-
GO:0030864cortical actin cytoskeletonISS16684770 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1371341411A,m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-149164816551A,m8hsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-208161916251Ahsa-miR-208AUAAGACGAGCAAAAAGCUUGU
miR-24164616531A,m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-29228422911A,m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-499161916251Ahsa-miR-499UUAAGACUUGCAGUGAUGUUUAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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