Gene Page: ILF2

Summary
GeneID  3608
Symbol  ILF2
Synonyms  MGC8391|NF45|PRO3063
Description  interleukin enhancer binding factor 2, 45kDa
See related  HGNC:6037|MIM:603181|Ensembl:ENSG00000143621|HPRD:04419|
Locus tag  RP11-354A16.1
Gene type  protein-coding
Map location  1q21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PAN20.850.85
STARD90.850.87
NEK90.830.81
MYO9B0.820.82
ACAD100.820.81
STAT20.810.84
PKD20.800.78
USP360.800.80
TRIM450.800.83
IKBKB0.800.78
Top 10 negatively co-expressed genes
AF347015.21-0.58-0.64
AF347015.31-0.57-0.57
IFI27-0.56-0.55
MT-CO2-0.52-0.53
AF347015.27-0.52-0.52
C1orf54-0.52-0.57
HIGD1B-0.52-0.52
VAMP5-0.51-0.55
METRN-0.51-0.53
GMFG-0.51-0.56
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIDA7519613 |10574923 
GO:0003702RNA polymerase II transcription factor activityTAS7519613 
GO:0003723RNA bindingIEA-
GO:0003725double-stranded RNA bindingIDA10574923 
GO:0005515protein bindingIPI9442054 |10574923 |11739746 
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006350transcriptionIEA-
GO:0006955immune responseIEA-
GO:0045893positive regulation of transcription, DNA-dependentIDA11739746 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA7519613 
GO:0005730nucleolusIDA11790298 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EEF1GEF1G | GIG35eukaryotic translation elongation factor 1 gammaTwo-hybridBioGRID16189514 
EIF2AK2EIF2AK1 | MGC126524 | PKR | PRKReukaryotic translation initiation factor 2-alpha kinase 2Biochemical ActivityBioGRID11438540 
ILF3CBTF | DRBF | DRBP76 | MMP4 | MPHOSPH4 | MPP4 | NF-AT-90 | NF110 | NF90 | NFAR | NFAR-1 | NFAR2 | TCP110 | TCP80interleukin enhancer binding factor 3, 90kDa-HPRD,BioGRID11739746 
PRKDCDNA-PKcs | DNAPK | DNPK1 | HYRC | HYRC1 | XRCC7 | p350protein kinase, DNA-activated, catalytic polypeptide-HPRD,BioGRID9442054 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD14559993 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-5052842901Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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