Gene Page

Gene Page: INSM1

Summary

GeneID

3642

Symbol

INSM1

Synonyms

IA-1|IA1

Description

insulinoma-associated 1

Locus tag

Gene type

protein-coding

Map location

20p11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.046

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

ADD2

0.92

0.94

DTX4

0.92

0.95

BCORL1

0.92

0.96

ZCCHC14

0.91

0.95

PIK3C2B

0.91

0.93

SRGAP2

0.91

0.95

ZNF398

0.91

0.95

ATXN7L1

0.90

0.94

KDM2B

0.90

0.96

CDK5R1

0.90

0.95

Top 10 negatively co-expressed genes

AF347015.31

-0.67

-0.89

S100B

-0.67

-0.85

C5orf53

-0.67

-0.77

TSC22D4

-0.66

-0.79

MT-CO2

-0.66

-0.89

AF347015.27

-0.66

-0.86

FXYD1

-0.66

-0.87

AIFM3

-0.66

-0.74

HEPN1

-0.65

-0.74

HLA-F

-0.65

-0.75

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003677

DNA binding

IEA

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

GO:0030154

cell differentiation

IEA

GO:0031018

endocrine pancreas development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
SORBS1	CAP \| DKFZp451C066 \| DKFZp586P1422 \| FLAF2 \| FLJ12406 \| KIAA1296 \| R85FL \| SH3D5 \| SH3P12 \| SORB1	sorbin and SH3 domain containing 1	-	HPRD,BioGRID	12079283
TUBB3	MC1R \| TUBB4 \| beta-4	tubulin, beta 3	Two-hybrid	BioGRID	16169070

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124/506	23	29	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	23	29	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-128	870	876	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	870	876	m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-142-5p	449	455	1A	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-151	351	357	1A	hsa-miR-151^brain	ACUAGACUGAAGCUCCUUGAGG
miR-186	573	579	1A	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-186	573	579	1A	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-23	540	546	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	540	546	1A	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-320	491	497	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-33	1021	1027	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	1021	1027	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-338	513	519	1A	hsa-miR-338^brain	UCCAGCAUCAGUGAUUUUGUUGA
miR-34b	662	668	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-375	544	550	1A	hsa-miR-375	UUUGUUCGUUCGGCUCGCGUGA
miR-493-5p	995	1001	1A	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-494	1090	1096	1A	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU
miR-99/100	412	418	m8	hsa-miR-99a^brain	AACCCGUAGAUCCGAUCUUGUG
				hsa-miR-100^brain	AACCCGUAGAUCCGAACUUGUG
				hsa-miR-99b^brain	CACCCGUAGAACCGACCUUGCG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.