Gene Page: ITGA2B

Summary
GeneID  3674
Symbol  ITGA2B
Synonyms  CD41|CD41B|GP2B|GPIIb|GTA|HPA3
Description  integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
See related  HGNC:6138|MIM:607759|Ensembl:ENSG00000005961|HPRD:06377|
Locus tag  -
Gene type  protein-coding
Map location  17q21.32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CNN10.820.74
TAGLN0.820.73
MYL90.810.74
ACTA20.790.72
DES0.770.67
ACTG20.700.61
MGP0.700.68
LMOD10.690.73
MYH110.660.71
MUSTN10.650.67
Top 10 negatively co-expressed genes
PPM1G-0.46-0.58
DBN1-0.46-0.57
ZNF821-0.46-0.57
NKIRAS2-0.45-0.57
HNRNPAB-0.45-0.59
TUBB2B-0.45-0.57
MARCKSL1-0.45-0.56
FUS-0.45-0.58
KIAA1949-0.45-0.53
GSTA4-0.45-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIEA-
GO:0042802identical protein bindingIPI15067009 
GO:0050840extracellular matrix bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007160cell-matrix adhesionIEA-
GO:0007155cell adhesionIEA-
GO:0007155cell adhesionTAS2439501 |10429193 
GO:0007229integrin-mediated signaling pathwayIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005925focal adhesionIEA-
GO:0009897external side of plasma membraneIEA-
GO:0005886plasma membraneEXP3607284 |10605720 
GO:0008305integrin complexIEA-
GO:0031092platelet alpha granule membraneEXP3607284 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AUP1-ancient ubiquitous protein 1-HPRD,BioGRID12042322 
CALRCRT | FLJ26680 | RO | SSA | cC1qRcalreticulin-HPRD7559457 
CD36CHDS7 | FAT | GP3B | GP4 | GPIV | PASIV | SCARB3CD36 molecule (thrombospondin receptor)Affinity Capture-WesternBioGRID11238109 
CIB1CIB | KIP | KIP1 | SIP2-28calcium and integrin binding 1 (calmyrin)-HPRD9030514 
CLNS1ACLCI | CLNS1B | IClnchloride channel, nucleotide-sensitive, 1AAffinity Capture-Western
Reconstituted Complex		BioGRID15075326 
COL1A2OI4collagen, type I, alpha 2-HPRD,BioGRID11359786 
COL2A1ANFH | AOM | COL11A3 | MGC131516 | SEDCcollagen, type II, alpha 1-HPRD,BioGRID7520045 |10772239 
F2PTcoagulation factor II (thrombin)-HPRD,BioGRID11487023 
FGAFib2 | MGC119422 | MGC119423 | MGC119425fibrinogen alpha chain-HPRD11460491 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD,BioGRID8631894 |11964172 
ITGB3CD61 | GP3A | GPIIIaintegrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Integrin-alphaIIb interacts with Integrin-beta3.BIND8132607 
-HPRD1429573 
VWFF8VWF | VWDvon Willebrand factor-HPRD1737795 
 


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