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|
| GeneID |
3684
|
| Symbol |
ITGAM
|
| Synonyms |
CD11B|CR3A|MAC-1|MAC1A|MGC117044|MO1A|SLEB6
|
| Description |
integrin, alpha M (complement component 3 receptor 3 subunit) |
| See related |
HGNC:6149|MIM:120980|HPRD:00411| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
16p11.2 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01775 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.2086 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| ATP13A4 | 0.87 | 0.75 | | |
| SLC4A4 | 0.85 | 0.83 | | |
| CGNL1 | 0.85 | 0.82 | | |
| CDGAP | 0.85 | 0.82 | | |
| ATP1A2 | 0.84 | 0.80 | | |
| PPARA | 0.83 | 0.70 | | |
| KANK1 | 0.82 | 0.76 | | |
| ACSS3 | 0.82 | 0.74 | | |
| BMPR1B | 0.82 | 0.73 | | |
| SASH1 | 0.81 | 0.82 | | |
Top 10 negatively co-expressed genes | | ZNF32 | -0.46 | -0.58 | | |
| COMMD3 | -0.43 | -0.51 | | |
| DCTN3 | -0.43 | -0.48 | | |
| RPL27 | -0.43 | -0.61 | | |
| C22orf32 | -0.43 | -0.58 | | |
| BID | -0.42 | -0.48 | | |
| DCTPP1 | -0.42 | -0.45 | | |
| LSM2 | -0.42 | -0.56 | | |
| AC034193.4 | -0.42 | -0.53 | | |
| RAB33A | -0.42 | -0.48 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000287 | magnesium ion binding | IEA | | - |
| GO:0004872 | receptor activity | IEA | | - |
| GO:0001948 | glycoprotein binding | IPI | | 15004192 |
| GO:0005509 | calcium ion binding | IEA | | - |
| GO:0005515 | protein binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007155 | cell adhesion | IEA | | - |
| GO:0007155 | cell adhesion | TAS | | 2563162 |
| GO:0007229 | integrin-mediated signaling pathway | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005794 | Golgi apparatus | IDA | | 18029348 |
| GO:0005634 | nucleus | IDA | | 18029348 |
| GO:0005737 | cytoplasm | IDA | | 18029348 |
| GO:0016020 | membrane | IEA | | - |
| GO:0016021 | integral to membrane | IEA | | - |
| GO:0008305 | integrin complex | IEA | | - |
| GO:0008305 | integrin complex | TAS | | 2563162 |
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