Gene Page: IVL

Summary
GeneID  3713
Symbol  IVL
Synonyms  -
Description  involucrin
See related  HGNC:6187|MIM:147360|Ensembl:ENSG00000163207|HPRD:00931|
Locus tag  -
Gene type  protein-coding
Map location  1q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NRXN10.870.90
INPP4A0.860.91
ATP9A0.860.92
GRM50.860.91
SRGAP30.850.90
MTMR90.850.90
NLGN4X0.840.87
AC073878.10.840.90
XKR40.840.89
CEP680.840.91
Top 10 negatively co-expressed genes
AF347015.31-0.62-0.73
FXYD1-0.61-0.69
HIGD1B-0.61-0.73
MT-CO2-0.61-0.73
AF347015.33-0.59-0.68
AC021016.1-0.59-0.69
MT-CYB-0.59-0.70
AF347015.8-0.58-0.72
TLCD1-0.57-0.65
S100B-0.57-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005198structural molecule activityIDA42494 |10908733 
GO:0030674protein binding, bridgingIDA10908733 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0010224response to UV-BIDA16639001 
GO:0018149peptide cross-linkingIDA10908733 
GO:0018153isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysineTAS1601889 
GO:0030216keratinocyte differentiationIDA10908733 
GO:0031424keratinizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001533cornified envelopeIDA10908733 
GO:0005737cytoplasmIDA42494 |16639001 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSTASTF1 | STFAcystatin A (stefin A)Reconstituted ComplexBioGRID8999895 
DSPDPI | DPIIdesmoplakinReconstituted ComplexBioGRID8999895 
EVPLEVPKenvoplakin-HPRD8999895 
IVL-involucrinReconstituted ComplexBioGRID8999895 
KRT1CK1 | EHK1 | K1 | KRT1Akeratin 1Reconstituted ComplexBioGRID8999895 
LORMGC111513loricrinReconstituted ComplexBioGRID8999895 
SPRR3-small proline-rich protein 3-HPRD11443109 
 


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