Gene Page: JAG2

Summary
GeneID  3714
Symbol  JAG2
Synonyms  HJ2|SER2
Description  jagged 2
See related  HGNC:6189|MIM:602570|Ensembl:ENSG00000184916|HPRD:03981|
Locus tag  -
Gene type  protein-coding
Map location  14q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CDH80.790.80
ST3GAL50.760.78
PEG3AS0.750.82
AL022165.20.750.77
PRKAG20.750.80
PAM0.750.76
TMTC10.740.83
ICMT0.740.80
DNAJC270.740.80
SLC9A70.740.76
Top 10 negatively co-expressed genes
AF347015.21-0.37-0.31
EMX2-0.36-0.55
C1orf61-0.35-0.41
IL32-0.35-0.38
SYCP3-0.34-0.39
CSAG1-0.34-0.35
AF347015.18-0.34-0.27
AP002478.3-0.34-0.36
SAT1-0.33-0.37
GNG11-0.33-0.36
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005112Notch bindingIPI9315665 
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIPI16713569 
GO:0008083growth factor activityIDA10383933 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001501skeletal system developmentIEA-
GO:0001709cell fate determinationNAS-
GO:0007154cell communicationIEA-
GO:0007283spermatogenesisIEP11700865 
GO:0007219Notch signaling pathwayNAS11056013 
GO:0009912auditory receptor cell fate commitmentISS10080181 
GO:0007049cell cycleNAS11549580 
GO:0007275multicellular organismal developmentIEA-
GO:0016331morphogenesis of embryonic epitheliumIEA-
GO:0042492gamma-delta T cell differentiationIEA-
GO:0042981regulation of apoptosisIEA-
GO:0030154cell differentiationIDA11549580 |11700865 
GO:0030155regulation of cell adhesionIEA-
GO:0042475odontogenesis of dentine-containing toothIEA-
GO:0042127regulation of cell proliferationIDA10383933 |11549580 
GO:0030334regulation of cell migrationNAS11549580 
GO:0045061thymic T cell selectionIDA10383933 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIEA-
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneISS10910909 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NOTCH1TAN1 | hN1Notch homolog 1, translocation-associated (Drosophila)-HPRD,BioGRID11006133 
NOTCH2AGS2 | hN2Notch homolog 2 (Drosophila)-HPRD,BioGRID10958687 
NOTCH3CADASIL | CASILNotch homolog 3 (Drosophila)-HPRD,BioGRID11006133 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/506798804m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1861481541Ahsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
hsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
miR-30-5p3243311A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-3811571641A,m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-4953013081A,m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.