Gene Page: KLK2

Summary
GeneID  3817
Symbol  KLK2
Synonyms  KLK2A2|MGC12201|hK2
Description  kallikrein-related peptidase 2
See related  HGNC:6363|MIM:147960|Ensembl:ENSG00000167751|HPRD:01006|
Locus tag  -
Gene type  protein-coding
Map location  19q13.41
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SMAD40.960.96
PAK20.950.97
SPAST0.950.96
GNA130.950.93
AP3M10.950.95
CAPRIN10.950.95
PHF160.950.92
PBRM10.950.96
ZNF8450.950.93
ZFP140.950.95
Top 10 negatively co-expressed genes
C5orf53-0.67-0.73
HLA-F-0.67-0.74
AIFM3-0.66-0.75
PTH1R-0.66-0.74
FXYD1-0.66-0.87
AF347015.31-0.66-0.85
MT-CO2-0.65-0.87
TNFSF12-0.65-0.65
AF347015.33-0.65-0.83
AF347015.27-0.65-0.82
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)10463585 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptorAR interacts with p-KLK-2.BIND15542435 
POLR2AMGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1polymerase (RNA) II (DNA directed) polypeptide A, 220kDaPol II interacts with p-KLK-2.BIND15542435 
SERPINA3AACT | ACT | GIG24 | GIG25 | MGC88254serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3-HPRD,BioGRID9042371 |9428387 
SERPINA4KAL | KLST | KST | PI4 | kallistatinserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4-HPRD,BioGRID10991942 
SERPINA5PAI3 | PCI | PLANH3 | PROCIserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5Affinity Capture-WesternBioGRID9016396 
-HPRD9368023 
SERPINB6CAP | DKFZp686I04222 | MGC111370 | MSTP057 | PI6 | PTI | SPI3serpin peptidase inhibitor, clade B (ovalbumin), member 6-HPRD,BioGRID11745444 
SERPINF2A2AP | AAP | ALPHA-2-PI | API | PLIserpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2-HPRD,BioGRID9042371 |9428387 
 


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