Gene Page: KLKB1

Summary
GeneID  3818
Symbol  KLKB1
Synonyms  KLK3|PPK
Description  kallikrein B, plasma (Fletcher factor) 1
See related  HGNC:6371|MIM:229000|Ensembl:ENSG00000164344|HPRD:01971|
Locus tag  -
Gene type  protein-coding
Map location  4q34-q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CAND10.960.97
NCBP10.960.95
IPO70.950.96
XRCC50.950.96
INTS70.950.95
ZMYM40.950.96
CAPRIN10.950.96
NUDT210.950.95
MATR30.950.96
SRP720.950.95
Top 10 negatively co-expressed genes
MT-CO2-0.76-0.88
AF347015.31-0.74-0.86
FXYD1-0.74-0.87
AF347015.33-0.73-0.85
MT-CYB-0.73-0.85
AF347015.8-0.73-0.87
AF347015.27-0.73-0.85
IFI27-0.72-0.85
AIFM3-0.72-0.79
HSD17B14-0.71-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)1993180 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisTAS1993180 
GO:0007596blood coagulationIEA-
GO:0006954inflammatory responseIEA-
GO:0042730fibrinolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS14718574 
GO:0005737cytoplasmIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
IGFBP3BP-53 | IBP3insulin-like growth factor binding protein 3-HPRD10226805 
KNG1BDK | KNGkininogen 1-HPRD,BioGRID291905 |7686159 
|7944388 |10464316 
SERPINA5PAI3 | PCI | PLANH3 | PROCIserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5-HPRD,BioGRID2551064 |11864713 
TFPI2FLJ21164 | PP5 | REF1 | TFPI-2tissue factor pathway inhibitor 2-HPRD8555184 
 


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