Gene Page: KNG1

Summary
GeneID  3827
Symbol  KNG1
Synonyms  BDK|KNG
Description  kininogen 1
See related  HGNC:6383|MIM:612358|Ensembl:ENSG00000113889|HPRD:01970|
Locus tag  -
Gene type  protein-coding
Map location  3q27
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SERPINF10.780.78
CHN10.760.82
KCNK10.760.79
PIP5K1B0.750.82
SLC17A70.750.70
CASQ10.750.71
RGS40.750.83
VSNL10.750.73
C8orf460.740.77
OSTF10.740.77
Top 10 negatively co-expressed genes
FADS2-0.49-0.59
SH3BP2-0.49-0.69
KIAA1949-0.48-0.59
BCL7C-0.48-0.66
SEMA4B-0.47-0.60
TRAF4-0.47-0.66
TUBB2B-0.47-0.63
SH2D2A-0.47-0.62
SH2B2-0.47-0.67
PDE9A-0.47-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005102receptor bindingIPINeurotransmitter (GO term level: 4)11290596 
GO:0004869cysteine protease inhibitor activityIEA-
GO:0008201heparin bindingNAS12911595 
GO:0008270zinc ion bindingNAS12911595 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007204elevation of cytosolic calcium ion concentrationIDA16014619 
GO:0007162negative regulation of cell adhesionIDA11970955 
GO:0030195negative regulation of blood coagulationIDA11970955 
GO:0006954inflammatory responseTAS11385996 
GO:0006939smooth muscle contractionTAS11385996 
GO:0043065positive regulation of apoptosisNAS12715893 
GO:0042311vasodilationIEA-
GO:0030146diuresisTAS11385996 
GO:0030147natriuresisTAS11385996 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005813centrosomeIDA18029348 
GO:0005576extracellular regionNAS14718574 
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APPAAA | ABETA | ABPP | AD1 | APPI | CTFgamma | CVAP | PN2amyloid beta (A4) precursor protein-HPRD12090937 
CAPN1CANP | CANP1 | CANPL1 | muCANP | muCLcalpain 1, (mu/I) large subunit-HPRD3038169 |8253784 
CAPN2CANP2 | CANPL2 | CANPml | FLJ39928 | mCANPcalpain 2, (m/II) large subunit-HPRD3038169 
CD93C1QR1 | C1qR(P) | C1qRP | CDw93 | MXRA4 | dJ737E23.1CD93 molecule-HPRD,BioGRID8710908 |12213329 
CTSGCG | MGC23078cathepsin G-HPRD11920276 
CTSL1CATL | CTSL | FLJ31037 | MEPcathepsin L1-HPRD11517935 
CTSSMGC3886cathepsin S-HPRD8706894 
ELA2GE | HLE | HNE | NE | PMN-Eelastase 2, neutrophil-HPRD,BioGRID12887060 
F11FXI | MGC141891coagulation factor XIReconstituted ComplexBioGRID291905 
-HPRD1652157 |3936495 
F2PTcoagulation factor II (thrombin)-HPRD1652157 
FTLMGC71996ferritin, light polypeptide-HPRD,BioGRID12071855 
GP1BABSS | CD42B | CD42b-alpha | GP1B | MGC34595glycoprotein Ib (platelet), alpha polypeptide-HPRD9269768 
ITGB2CD18 | LAD | LCAMB | LFA-1 | MAC-1 | MF17 | MFI7integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)-HPRD,BioGRID10845911 
KLKB1KLK3 | PPKkallikrein B, plasma (Fletcher factor) 1-HPRD,BioGRID291905 |7686159 
|7944388 |10464316 
KRT1CK1 | EHK1 | K1 | KRT1Akeratin 1-HPRD,BioGRID10066772 
PLAURCD87 | UPAR | URKRplasminogen activator, urokinase receptor-HPRD,BioGRID14764580 
PLGDKFZp779M0222plasminogen-HPRD,BioGRID9428707 
RXFP4GPCR142 | GPR100 | MGC126556 | MGC126558 | RLN3R2 | RXFPR4relaxin/insulin-like family peptide receptor 4-HPRD14530218 
THBS1THBS | TSP | TSP1thrombospondin 1-HPRD9459346 
VTNV75 | VN | VNTvitronectin-HPRD,BioGRID10887113 
 


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