Gene Page: RND3

Summary
GeneID  390
Symbol  RND3
Synonyms  ARHE|Rho8|RhoE|memB
Description  Rho family GTPase 3
See related  HGNC:671|MIM:602924|Ensembl:ENSG00000115963|HPRD:04233|
Locus tag  -
Gene type  protein-coding
Map location  2q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AC004410.10.720.72
TYK20.710.73
CCHCR10.680.65
LRCH40.680.72
C2orf810.670.64
PCSK40.670.69
LRDD0.670.69
RFNG0.670.71
C16orf480.670.64
RGL20.670.63
Top 10 negatively co-expressed genes
AF347015.27-0.42-0.45
AF347015.31-0.42-0.43
MT-CYB-0.41-0.43
AF347015.21-0.40-0.46
MT-CO2-0.40-0.42
AF347015.8-0.39-0.41
AF347015.33-0.37-0.39
MT-ATP8-0.37-0.46
AF347015.2-0.36-0.40
AF347015.15-0.36-0.39
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003924GTPase activityTAS8649376 
GO:0005525GTP bindingTAS8649376 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionTAS9531558 
GO:0007264small GTPase mediated signal transductionIEA-
GO:0030036actin cytoskeleton organizationTAS9531558 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005622intracellularIEA-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARHGAP5GFI2 | RhoGAP5 | p190-BRho GTPase activating protein 5Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID12842009 
CITCRIK | KIAA0949 | STK21citron (rho-interacting, serine/threonine kinase 21)Two-hybridBioGRID12773565 
PLXNB1KIAA0407 | MGC149167 | PLEXIN-B1 | PLXN5 | SEPplexin B1Reconstituted ComplexBioGRID12730235 
ROCK1MGC131603 | MGC43611 | P160ROCK | PRO0435Rho-associated, coiled-coil containing protein kinase 1-HPRD,BioGRID12773565 
SFNYWHASstratifinAffinity Capture-MSBioGRID15778465 
UBXN11COA-1 | DKFZp686F04228 | PP2243 | SOC | SOCI | UBXD5UBX domain protein 11-HPRD,BioGRID11940653 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1284474541A,m8hsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-200bc/429158415911A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-2059149201Ahsa-miR-205UCCUUCAUUCCACCGGAGUCUG
miR-224214220m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-262172231Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-27448454m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-29313319m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-30-5p127212781Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-33015751581m8hsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
miR-409-5p177217781Ahsa-miR-409-5pAGGUUACCCGAGCAACUUUGCA
miR-49517071713m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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