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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: LBR

Summary

GeneID

3930

Symbol

LBR

Synonyms

DHCR14B|FLJ43126|LMN2R|MGC9041|PHA

Description

lamin B receptor

Locus tag

Gene type

protein-coding

Map location

1q42.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0057

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SLC12A4

0.79

0.80

RFX4

0.78

0.80

LRIG1

0.77

0.76

FKBP10

0.76

0.85

SIX5

0.76

0.81

GLI1

0.75

0.68

TRIP6

0.75

0.78

C18orf51

0.75

0.78

BMP7

0.74

0.77

PDLIM3

0.74

0.72

Top 10 negatively co-expressed genes

FBXW7

-0.44

-0.53

SLC26A4

-0.40

-0.54

SEH1L

-0.40

-0.52

LNX1

-0.39

-0.47

ELMOD1

-0.39

-0.45

ARHGAP20

-0.38

-0.46

DYNC1I1

-0.38

-0.46

SH3GL2

-0.38

-0.46

PRKACB

-0.38

-0.49

CAP2

-0.38

-0.44

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

GO:0003677

DNA binding

TAS

8157662

GO:0005521

lamin binding

TAS

8157662

GO:0050613

delta14-sterol reductase activity

EXP

12618959

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005635

nuclear envelope

EXP

12618959

GO:0005637

nuclear inner membrane

IEA

GO:0005639

integral to nuclear inner membrane

TAS

8157662

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IDA

15698635

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AKAP8L	DKFZp434L0650 \| HA95 \| HAP95 \| NAKAP \| NAKAP95	A kinase (PRKA) anchor protein 8-like	-	HPRD,BioGRID	11034899
CBX3	HECH \| HP1-GAMMA \| HP1Hs-gamma	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	-	HPRD,BioGRID	8663349
CBX5	HP1 \| HP1A	chromobox homolog 5 (HP1 alpha homolog, Drosophila)	-	HPRD,BioGRID	8663349
FNBP4	DKFZp686M14102 \| DKFZp779I1064 \| FBP30 \| FLJ41904 \| KIAA1014	formin binding protein 4	-	HPRD,BioGRID	10744724
LMNB1	ADLD \| LMN \| LMN2 \| LMNB \| MGC111419	lamin B1	-	HPRD,BioGRID	12490158
SRPK1	SFRSK1	SFRS protein kinase 1	-	HPRD	10049757 \|10390541
YWHAG	14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	Affinity Capture-MS	BioGRID	17353931

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-148/152	88	95	1A,m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-181	667	673	m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-223	91	97	1A	hsa-miR-223	UGUCAGUUUGUCAAAUACCCC
miR-23	669	675	m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	669	675	m8	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-323	669	675	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-378	126	132	m8	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.