|
|
| GeneID |
4056
|
| Symbol |
LTC4S
|
| Synonyms |
MGC33147
|
| Description |
leukotriene C4 synthase |
| See related |
HGNC:6719|MIM:246530|Ensembl:ENSG00000213316|HPRD:02004| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
5q35 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.0276 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| OTX2 | 0.85 | 0.48 | | |
| TAL1 | 0.81 | 0.24 | | |
| MC4R | 0.76 | 0.17 | | |
| ANO2 | 0.75 | 0.18 | | |
| CEACAM21 | 0.72 | 0.27 | | |
| PDE5A | 0.72 | 0.29 | | |
| TRH | 0.72 | 0.34 | | |
| AC097067.1 | 0.71 | 0.21 | | |
| SP5 | 0.70 | 0.13 | | |
| LEF1 | 0.70 | 0.24 | | |
Top 10 negatively co-expressed genes | | SPARCL1 | -0.25 | -0.28 | | |
| CXCL14 | -0.24 | -0.45 | | |
| SLC16A11 | -0.23 | -0.26 | | |
| GRASP | -0.23 | -0.35 | | |
| TMEM54 | -0.23 | -0.21 | | |
| COX4I2 | -0.22 | -0.35 | | |
| RGS20 | -0.22 | -0.33 | | |
| TNFSF12 | -0.22 | -0.26 | | |
| C5orf53 | -0.22 | -0.37 | | |
| TINAGL1 | -0.22 | -0.26 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004364 | glutathione transferase activity | TAS | | 8052639 |
| GO:0004464 | leukotriene-C4 synthase activity | TAS | | 8052639 |
| GO:0016829 | lyase activity | IEA | | - |
| GO:0008047 | enzyme activator activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0019370 | leukotriene biosynthetic process | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005792 | microsome | TAS | | 1454853 |
| GO:0005624 | membrane fraction | TAS | | 8052639 |
| GO:0016020 | membrane | IEA | | - |
| GO:0016021 | integral to membrane | TAS | | 8052639 |
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