Gene Page: LTF

Summary
GeneID  4057
Symbol  LTF
Synonyms  GIG12|HLF2|LF
Description  lactotransferrin
See related  HGNC:6720|MIM:150210|Ensembl:ENSG00000012223|HPRD:01028|
Locus tag  -
Gene type  protein-coding
Map location  3p21.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZCCHC30.900.93
YY10.890.93
SFPQ0.880.91
HNRNPL0.880.89
MEX3D0.880.91
NUDT110.880.92
EIF4A30.870.87
HNRNPM0.870.87
HNRNPAB0.870.89
NUDT100.860.90
Top 10 negatively co-expressed genes
HLA-F-0.69-0.76
C5orf53-0.68-0.76
MT-CO2-0.67-0.85
AF347015.31-0.66-0.83
AF347015.33-0.66-0.83
S100B-0.66-0.79
AF347015.27-0.66-0.82
MT-CYB-0.65-0.83
FXYD1-0.64-0.80
AF347015.8-0.64-0.84
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)9770539 
GO:0008199ferric iron bindingIEA-
GO:0008233peptidase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006826iron ion transportIEA-
GO:0006811ion transportIEA-
GO:0006959humoral immune responseTAS9770539 
GO:0006879cellular iron ion homeostasisIEA-
GO:0042742defense response to bacteriumIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD14-CD14 molecule-HPRD,BioGRID11083760 
CEBPAC/EBP-alpha | CEBPCCAAT/enhancer binding protein (C/EBP), alphaC/EBP-alpha interacts with the lactoferrin promoter.BIND15588942 
CEBPDC/EBP-delta | CELF | CRP3 | NF-IL6-betaCCAAT/enhancer binding protein (C/EBP), deltaC/EBP-delta interacts with the lactoferrin promoter.BIND15588942 
CEBPEC/EBP-epsilon | CRP1CCAAT/enhancer binding protein (C/EBP), epsilonC/EBP-epsilon interacts with the lactoferrin promoter.BIND15588942 
CPCP-2ceruloplasmin (ferroxidase)-HPRD,BioGRID10666301 
ITLN1FLJ20022 | HL-1 | HL1 | INTL | ITLN | LFR | hIntL | omentinintelectin 1 (galactofuranose binding)-HPRD11313366 
LCN1MGC71975 | PMFA | TP | VEGPlipocalin 1 (tear prealbumin)-HPRD10558865 
LRP1A2MR | APOER | APR | CD91 | FLJ16451 | IGFBP3R | LRP | MGC88725 | TGFBR5low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)-HPRD1464627 
LYZLZMlysozyme (renal amyloidosis)-HPRD,BioGRID9359845 
MUC7DKFZp686J03256 | FLJ27047 | MG2 | MGC34772mucin 7, secreted-HPRD,BioGRID12766201 
SGK1SGKserum/glucocorticoid regulated kinase 1Affinity Capture-MSBioGRID17353931 
 


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