Gene Page

Gene Page: ACCN2

Summary

GeneID

Symbol

ACCN2

Synonyms

ASIC|ASIC1|ASIC1A|BNaC2|hBNaC2

Description

amiloride-sensitive cation channel 2, neuronal

Locus tag

Gene type

protein-coding

Map location

12q12

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0024

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005509

calcium ion binding

IEA

GO:0005515

protein binding

IPI

11802773

GO:0005216

ion channel activity

IEA

GO:0015280

amiloride-sensitive sodium channel activity

NAS

GO:0031402

sodium ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007165

signal transduction

TAS

9037075

GO:0009268

response to pH

TAS

9062189

GO:0006816

calcium ion transport

IEA

GO:0006814

sodium ion transport

NAS

9037075

GO:0006811

ion transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005886

plasma membrane

IEA

GO:0005887

integral to plasma membrane

TAS

9037075

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACCN1	ACCN \| ASIC2 \| ASIC2a \| BNC1 \| BNaC1 \| MDEG \| hBNaC1	amiloride-sensitive cation channel 1, neuronal	-	HPRD	9360943
ACCN2	ASIC \| ASIC1 \| ASIC1A \| BNaC2 \| hBNaC2	amiloride-sensitive cation channel 2, neuronal	-	HPRD,BioGRID	11512022
PICK1	MGC15204 \| PICK \| PRKCABP	protein interacting with PRKCA 1	PICK1 interacts with ASIC.	BIND	11802773
PICK1	MGC15204 \| PICK \| PRKCABP	protein interacting with PRKCA 1	-	HPRD,BioGRID	11739374 \|11802773 \|12578970
PRKACA	MGC102831 \| MGC48865 \| PKACA	protein kinase, cAMP-dependent, catalytic, alpha	Biochemical Activity	BioGRID	12578970
STOML1	FLJ36370 \| SLP-1 \| STORP \| hUNC-24	stomatin (EPB72)-like 1	Affinity Capture-Western	BioGRID	15471860

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	1092	1098	m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-124.1	1254	1260	1A	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124.1	1254	1260	1A	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-125/351	744	751	1A,m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	744	751	1A,m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-134	348	354	m8	hsa-miR-134^brain	UGUGACUGGUUGACCAGAGGG
miR-181	420	426	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-218	1118	1125	1A,m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-27	1180	1186	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	1180	1186	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-29	621	627	m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-326	415	421	1A	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-338	673	679	1A	hsa-miR-338^brain	UCCAGCAUCAGUGAUUUUGUUGA
miR-380-5p	1956	1962	1A	hsa-miR-380-5p	UGGUUGACCAUAGAACAUGCGC
miR-380-5p	1956	1962	1A	hsa-miR-563	AGGUUGACAUACGUUUCCC
miR-9	353	359	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA
miR-9	353	359	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.