Gene Page: MEP1A

Summary
GeneID  4224
Symbol  MEP1A
Synonyms  PPHA
Description  meprin A, alpha (PABA peptide hydrolase)
See related  HGNC:7015|MIM:600388|Ensembl:ENSG00000112818|HPRD:02666|
Locus tag  -
Gene type  protein-coding
Map location  6p12-p11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATRN0.930.96
ADAR0.920.95
GSK3B0.910.94
MYO9A0.910.95
LARP4B0.910.94
GPR1070.910.94
ATP9A0.910.94
KPNA60.910.93
KIAA12190.910.94
ARHGEF70.900.94
Top 10 negatively co-expressed genes
FXYD1-0.69-0.74
AF347015.31-0.68-0.75
MT-CO2-0.66-0.74
HIGD1B-0.65-0.74
AF347015.21-0.65-0.77
TLCD1-0.65-0.70
AC021016.1-0.64-0.70
AF347015.33-0.63-0.68
AF347015.8-0.63-0.72
CLDN10-0.63-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004222metalloendopeptidase activityTAS9288916 
GO:0008270zinc ion bindingIEA-
GO:0008233peptidase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0007586digestionTAS9288916 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005615extracellular spaceTAS8262185 
GO:0005625soluble fractionTAS8262185 
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS8262185 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AGTANHU | FLJ92595 | FLJ97926 | SERPINA8angiotensinogen (serpin peptidase inhibitor, clade A, member 8)-HPRD11278902 
BDKRB1B1BKR | B1R | BKB1R | BKR1 | BRADYB1bradykinin receptor B1Biochemical ActivityBioGRID11278902 
FN1CIG | DKFZp686F10164 | DKFZp686H0342 | DKFZp686I1370 | DKFZp686O13149 | ED-B | FINC | FN | FNZ | GFND | GFND2 | LETS | MSFfibronectin 1-HPRD,BioGRID8063866 
GGCTC7orf24 | CRF21 | FLJ11717 | GCTG | Ggc | MGC3077gamma-glutamyl cyclotransferaseBiochemical ActivityBioGRID11278902 
GNRH1GNRH | GRH | LHRH | LNRHgonadotropin-releasing hormone 1 (luteinizing-releasing hormone)Biochemical ActivityBioGRID11278902 
LAMA1LAMAlaminin, alpha 1-HPRD,BioGRID10620696 
LAMA5KIAA1907laminin, alpha 5-HPRD,BioGRID10620696 
MEP1APPHAmeprin A, alpha (PABA peptide hydrolase)-HPRD,BioGRID11301339 
MEP1B-meprin A, beta-HPRD8760356 
NPYPYY4neuropeptide YBiochemical ActivityBioGRID11278902 
NTSNMN-125 | NN | NT | NT/N | NTS1neurotensinBiochemical ActivityBioGRID11278902 
PTHPTH1parathyroid hormone-HPRD,BioGRID11278902 
VIPMGC13587 | PHM27vasoactive intestinal peptideBiochemical ActivityBioGRID11278902 
 


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