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|
| GeneID |
4317
|
| Symbol |
MMP8
|
| Synonyms |
CLG1|HNC|PMNL-CL
|
| Description |
matrix metallopeptidase 8 (neutrophil collagenase) |
| See related |
HGNC:7175|MIM:120355|Ensembl:ENSG00000118113|HPRD:00385| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
11q22.3 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| NFKB2 | 0.75 | 0.77 | | |
| TEAD3 | 0.74 | 0.72 | | |
| INPPL1 | 0.74 | 0.74 | | |
| ARHGEF1 | 0.74 | 0.69 | | |
| ECHDC2 | 0.73 | 0.71 | | |
| PLD2 | 0.73 | 0.71 | | |
| C20orf175 | 0.72 | 0.72 | | |
| FKBP10 | 0.71 | 0.71 | | |
| SIX5 | 0.71 | 0.71 | | |
| LAMB2 | 0.71 | 0.74 | | |
Top 10 negatively co-expressed genes | | GPR22 | -0.48 | -0.54 | | |
| EIF4A2 | -0.43 | -0.49 | | |
| C20orf7 | -0.43 | -0.53 | | |
| PPP3CB | -0.42 | -0.45 | | |
| SEH1L | -0.42 | -0.48 | | |
| TMEM70 | -0.42 | -0.42 | | |
| PRKACB | -0.41 | -0.44 | | |
| FBXW7 | -0.41 | -0.44 | | |
| CAPZA2 | -0.41 | -0.50 | | |
| RALYL | -0.41 | -0.45 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004252 | serine-type endopeptidase activity | IDA | glutamate (GO term level: 7) | 2164002 |16192646 |
| GO:0005509 | calcium ion binding | IEA | | - |
| GO:0004222 | metalloendopeptidase activity | IEA | | - |
| GO:0008270 | zinc ion binding | TAS | | 2164002 |
| GO:0008233 | peptidase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006508 | proteolysis | IDA | | 2164002 |
| GO:0008152 | metabolic process | IEA | | - |
| GO:0030574 | collagen catabolic process | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | IEA | | - |
| GO:0005578 | proteinaceous extracellular matrix | IEA | | - |
| GO:0005615 | extracellular space | IDA | | 2164002 |
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