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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MMP14

Summary

GeneID

4323

Symbol

MMP14

Synonyms

MMP-X1|MT1-MMP|MTMMP1

Description

matrix metallopeptidase 14 (membrane-inserted)

Locus tag

Gene type

protein-coding

Map location

14q11-q12

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.047

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005509

calcium ion binding

IEA

GO:0005515

protein binding

IPI

14718544

GO:0004222

metalloendopeptidase activity

TAS

8015608

GO:0008270

zinc ion binding

TAS

8015608

GO:0008233

peptidase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006508

proteolysis

TAS

8015608

GO:0008152

metabolic process

IEA

GO:0016477

cell migration

IEA

GO:0031638

zymogen activation

IEA

GO:0048754

branching morphogenesis of a tube

IEA

GO:0030324

lung development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005578

proteinaceous extracellular matrix

IEA

GO:0016020

membrane

IEA

GO:0005887

integral to plasma membrane

TAS

8015608

GO:0042470

melanosome

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ADI1	APL1 \| ARD \| FLJ10913 \| HMFT1638 \| MTCBP-1 \| MTCBP1 \| SIP-L \| SIPL	acireductone dioxygenase 1	-	HPRD	14718544
C1QBP	GC1QBP \| HABP1 \| SF2p32 \| gC1Q-R \| gC1qR \| p32	complement component 1, q subcomponent binding protein	-	HPRD,BioGRID	12220632
CLDN1	CLD1 \| ILVASC \| SEMP1	claudin 1	-	HPRD	11382769
ITGB8	-	integrin, beta 8	-	HPRD	11970960
LRP1	A2MR \| APOER \| APR \| CD91 \| FLJ16451 \| IGFBP3R \| LRP \| MGC88725 \| TGFBR5	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	-	HPRD,BioGRID	14645246
LUM	LDC \| SLRR2D	lumican	-	HPRD,BioGRID	15466200
SPOCK1	FLJ37170 \| SPOCK \| TESTICAN \| TIC1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	-	HPRD	12810672
SPOCK3	HSAJ1454 \| TES-3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	-	HPRD,BioGRID	11751414
TIMP2	CSC-21K	TIMP metallopeptidase inhibitor 2	-	HPRD,BioGRID	9422789
TIMP3	HSMRK222 \| K222 \| K222TA2 \| SFD	TIMP metallopeptidase inhibitor 3	-	HPRD	8663332

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-150	1381	1388	1A,m8	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG
miR-181	291	297	m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-24	669	676	1A,m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-26	312	318	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	312	318	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-369-3p	1529	1535	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-369-3p	1529	1535	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-374	1529	1536	1A,m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-374	1529	1536	1A,m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-410	1540	1546	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.