Gene Page: MYF5

Summary
GeneID  4617
Symbol  MYF5
Synonyms  bHLHc2
Description  myogenic factor 5
See related  HGNC:7565|MIM:159990|Ensembl:ENSG00000111049|HPRD:01168|
Locus tag  -
Gene type  protein-coding
Map location  12q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
USP540.770.80
C1orf1980.760.77
MYO1D0.750.74
THBS20.750.73
ADIPOR20.740.75
ATP11A0.740.75
NPC10.740.75
JAM30.740.75
FNBP10.730.74
RNF1300.730.71
Top 10 negatively co-expressed genes
ST20-0.42-0.49
AC044839.2-0.39-0.37
C1orf61-0.39-0.38
TIMM8B-0.38-0.47
C16orf14-0.37-0.41
TTC9B-0.36-0.41
UQCR-0.36-0.47
ENHO-0.36-0.35
UQCRQ-0.36-0.40
NPPA-0.35-0.31
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003705RNA polymerase II transcription factor activity, enhancer bindingTAS2311584 
GO:0030528transcription regulator activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007519skeletal muscle developmentTASneuron (GO term level: 8)2721498 
GO:0001756somitogenesisIEA-
GO:0001952regulation of cell-matrix adhesionIEA-
GO:0006357regulation of transcription from RNA polymerase II promoterTAS2311584 
GO:0007517muscle developmentTAS2311584 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0030198extracellular matrix organizationIEA-
GO:0048704embryonic skeletal system morphogenesisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD10757985 
CALM2CAMII | PHKD | PHKD2calmodulin 2 (phosphorylase kinase, delta)-HPRD10757985 
CALM3PHKD | PHKD3calmodulin 3 (phosphorylase kinase, delta)-HPRD10757985 
ELSPBP1E12 | HE12epididymal sperm binding protein 1Two-hybridBioGRID9242638 
ID1ID | bHLHb24inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinTwo-hybridBioGRID9242638 
ID2GIG8 | ID2A | ID2H | MGC26389 | bHLHb26inhibitor of DNA binding 2, dominant negative helix-loop-helix protein-HPRD,BioGRID9242638 
ID3HEIR-1 | bHLHb25inhibitor of DNA binding 3, dominant negative helix-loop-helix protein-HPRD,BioGRID9242638 
MDFII-MF | I-mfaMyoD family inhibitorAffinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID8797820 
MYF5bHLHc2myogenic factor 5-HPRD9242638 
TCF3E2A | ITF1 | MGC129647 | MGC129648 | bHLHb21transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)Two-hybridBioGRID9242638 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p1391461A,m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-17-5p/20/93.mr/106/519.d1381441Ahsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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