Gene Page: NIT1

Summary
GeneID  4817
Symbol  NIT1
Synonyms  MGC57670
Description  nitrilase 1
See related  HGNC:7828|MIM:604618|Ensembl:ENSG00000158793|HPRD:07056|
Locus tag  -
Gene type  protein-coding
Map location  1q21-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EPC10.970.96
HNRNPR0.960.95
GART0.960.93
DHX90.960.95
ARFGAP30.960.96
DDX50.960.96
ZNF5120.960.96
SLC39A60.960.95
FUBP10.960.96
DHX570.960.96
Top 10 negatively co-expressed genes
AIFM3-0.79-0.85
HLA-F-0.78-0.83
FXYD1-0.78-0.93
AF347015.31-0.78-0.90
TSC22D4-0.77-0.86
MT-CO2-0.77-0.91
IFI27-0.77-0.92
AF347015.33-0.76-0.88
S100B-0.76-0.85
C5orf53-0.76-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000257nitrilase activityTAS9671749 
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008150biological_processND-
GO:0006807nitrogen compound metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
XRCC6CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAAX-ray repair complementing defective repair in Chinese hamster cells 6Two-hybridBioGRID16169070 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2246975m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-4102142201Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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