Gene Page: NKX3-1

Summary
GeneID  4824
Symbol  NKX3-1
Synonyms  BAPX2|NKX3|NKX3.1|NKX3A
Description  NK3 homeobox 1
See related  HGNC:7838|MIM:602041|Ensembl:ENSG00000167034|HPRD:03620|
Locus tag  -
Gene type  protein-coding
Map location  8p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STARD80.740.74
DOCK60.730.73
NOS30.730.75
MFSD20.730.72
ROBO40.710.74
TIE10.710.71
SCARF10.710.76
ENG0.700.71
CDH50.700.69
SIPA10.690.71
Top 10 negatively co-expressed genes
MTIF3-0.47-0.46
CRYZL1-0.44-0.44
RWDD1-0.44-0.47
THOC7-0.42-0.43
CCNH-0.40-0.38
MRPS18C-0.40-0.44
GTPBP10-0.40-0.38
UQCRB-0.40-0.46
ZCRB1-0.40-0.43
RPL36AL-0.40-0.39
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityNAS11137288 
GO:0008134transcription factor bindingIEA-
GO:0016563transcription activator activityIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentNAS11137288 
GO:0007431salivary gland developmentIEA-
GO:0007275multicellular organismal developmentTAS9537602 
GO:0030850prostate gland developmentIEA-
GO:0048754branching morphogenesis of a tubeIEA-
GO:0050680negative regulation of epithelial cell proliferationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusNAS11137288 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SPDEFPDEF | RP11-375E1__A.3 | bA375E1.3SAM pointed domain containing ets transcription factor-HPRD,BioGRID11809674 
SRFMCM1serum response factor (c-fos serum response element-binding transcription factor)-HPRD,BioGRID10993896 
 


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