Gene Page: ACR

Summary
GeneID  49
Symbol  ACR
Synonyms  -
Description  acrosin
See related  HGNC:126|MIM:102480|Ensembl:ENSG00000100312|HPRD:06342|
Locus tag  -
Gene type  protein-coding
Map location  22q13-qter|22q13.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TTRAP0.890.84
STRAP0.890.84
RAN0.870.84
PSMD60.860.80
AP3S20.860.83
GFM20.860.83
RTCD10.860.81
NIPA20.860.80
TRMT120.860.83
C20orf430.860.82
Top 10 negatively co-expressed genes
AF347015.2-0.73-0.58
AF347015.8-0.72-0.60
MT-CO2-0.72-0.58
AF347015.26-0.71-0.59
AF347015.21-0.71-0.57
MT-CYB-0.71-0.59
AF347015.33-0.70-0.59
AF347015.15-0.69-0.59
AF347015.31-0.69-0.58
AF347015.18-0.68-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIDAglutamate (GO term level: 7)6802470 
GO:0003677DNA bindingNAS1937464 
GO:0004040amidase activityISS-
GO:0005537mannose bindingIDA15950652 
GO:0005507copper ion bindingNAS6815104 
GO:0005515protein bindingIPI7521127 |15950651 
GO:0005515protein bindingISS-
GO:0008270zinc ion bindingNAS6815104 
GO:0008144drug bindingISS-
GO:0008233peptidase activityIEA-
GO:0042806fucose bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002077acrosome matrix dispersalNAS10418103 
GO:0007190activation of adenylate cyclase activityIDA3880736 
GO:0007341penetration of zona pellucidaIDA10369396 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0043234protein complexIDA7521127 
GO:0043159acrosomal matrixTAS12398221 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
E2F4E2F-4E2F transcription factor 4, p107/p130-bindingE2F4 interacts with ACR promoter.BIND15782160 
SERPINA5PAI3 | PCI | PLANH3 | PROCIserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5-HPRD,BioGRID7521127 
ZP2ZPAzona pellucida glycoprotein 2 (sperm receptor)-HPRD11739644 
 


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