Gene Page: NTS

Summary
GeneID  4922
Symbol  NTS
Synonyms  NMN-125|NN|NT|NT/N|NTS1
Description  neurotensin
See related  HGNC:8038|MIM:162650|Ensembl:ENSG00000133636|HPRD:08878|
Locus tag  -
Gene type  protein-coding
Map location  12q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenics, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KDM10.970.91
NONO0.960.90
ILF20.960.94
NUP880.960.92
XRN20.960.90
RBMX0.960.93
SNRNP400.950.92
APEX10.950.95
EIF3L0.950.95
EEF1A10.950.94
Top 10 negatively co-expressed genes
HLA-F-0.70-0.80
C5orf53-0.69-0.73
AIFM3-0.69-0.77
FBXO2-0.68-0.67
PTH1R-0.68-0.72
AF347015.27-0.66-0.86
ALDOC-0.66-0.69
HEPN1-0.66-0.77
LDHD-0.66-0.67
TINAGL1-0.66-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005184neuropeptide hormone activityIEAaxon, Synap, Brain, Neurotransmitter (GO term level: 6)-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionNAS8954810 
GO:0050880regulation of blood vessel sizeIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005625soluble fractionTAS8954810 
GO:0031410cytoplasmic vesicleIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2-HPRD12473660 
MEP1APPHAmeprin A, alpha (PABA peptide hydrolase)Biochemical ActivityBioGRID11278902 
NTSR1NTRneurotensin receptor 1 (high affinity)-HPRD,BioGRID11559354 
NTSR2NTR2neurotensin receptor 2-HPRD11801734 
SORT1Gp95 | NT3sortilin 1in vivoBioGRID9756851 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_AP1_PATHWAY 7060All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP 185126All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP 157104All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP 4430All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_DN 240171All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN 9558All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_E 8944All SZGR genes in this pathway
BENPORATH_ES_1 379235All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_2 11476All SZGR genes in this pathway
STOSSI_RESPONSE_TO_ESTRADIOL 5035All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP 156101All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
MCCOLLUM_GELDANAMYCIN_RESISTANCE_DN 76All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 19693All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
CROMER_TUMORIGENESIS_UP 6336All SZGR genes in this pathway
LEE_LIVER_CANCER_SURVIVAL_DN 175103All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_UP 7349All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
DALESSIO_TSA_RESPONSE 2916All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway


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