Gene Page: OGG1

Summary
GeneID  4968
Symbol  OGG1
Synonyms  HMMH|HOGG1|MUTM|OGH1
Description  8-oxoguanine DNA glycosylase
See related  HGNC:8125|MIM:601982|Ensembl:ENSG00000114026|HPRD:03582|
Locus tag  -
Gene type  protein-coding
Map location  3p26.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RG9MTD10.920.92
MRPS350.910.91
UBA30.890.88
COPS30.890.90
FARSB0.890.87
PTGES30.890.88
UTP180.880.88
GGPS10.880.89
MRPL30.880.88
CCNC0.880.87
Top 10 negatively co-expressed genes
AF347015.8-0.73-0.71
AF347015.26-0.73-0.72
AF347015.2-0.72-0.70
AF347015.15-0.72-0.71
MT-CYB-0.72-0.70
AF347015.33-0.72-0.70
MT-CO2-0.71-0.68
AF347015.27-0.69-0.66
AF347015.31-0.67-0.66
GPT-0.65-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003824catalytic activityIEA-
GO:0003684damaged DNA bindingTAS9223305 
GO:0005515protein bindingIPI15518571 
GO:0004519endonuclease activityTAS9223305 
GO:0016798hydrolase activity, acting on glycosyl bondsIEA-
GO:0016829lyase activityIEA-
GO:0008534oxidized purine base lesion DNA N-glycosylase activityEXP10583946 
GO:0008534oxidized purine base lesion DNA N-glycosylase activityNAS10717238 
GO:0008534oxidized purine base lesion DNA N-glycosylase activityTAS9190902 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006289nucleotide-excision repairIEA-
GO:0006284base-excision repairIEA-
GO:0006284base-excision repairTAS9190902 
GO:0008152metabolic processIEA-
GO:0045007depurinationEXP10583946 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP10583946 
GO:0005654nucleoplasmTAS9223305 
GO:0005739mitochondrionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHGBSCG1chromogranin B (secretogranin 1)Two-hybridBioGRID16169070 
PRKCAAAG6 | MGC129900 | MGC129901 | PKC-alpha | PKCA | PRKACAprotein kinase C, alpha-HPRD,BioGRID12034821 
SNRPFSMFsmall nuclear ribonucleoprotein polypeptide FAffinity Capture-MSBioGRID17353931 
XRCC1RCCX-ray repair complementing defective repair in Chinese hamster cells 1Reconstituted Complex
Two-hybrid
BioGRID12933815 
 


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