|
|
| GeneID |
5023
|
| Symbol |
P2RX1
|
| Synonyms |
P2X1
|
| Description |
purinergic receptor P2X, ligand-gated ion channel, 1 |
| See related |
HGNC:8533|MIM:600845|Ensembl:ENSG00000108405|HPRD:07526| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
17p13.3 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| ABCC12 | 0.75 | 0.70 | | |
| CASQ1 | 0.65 | 0.69 | | |
| NRSN1 | 0.65 | 0.68 | | |
| TMEM155 | 0.65 | 0.72 | | |
| CHN1 | 0.65 | 0.68 | | |
| EPHX4 | 0.65 | 0.69 | | |
| SMYD2 | 0.64 | 0.70 | | |
| RHEBL1 | 0.64 | 0.72 | | |
| AQP9 | 0.64 | 0.65 | | |
| NRN1 | 0.64 | 0.71 | | |
Top 10 negatively co-expressed genes | | GLIS2 | -0.40 | -0.48 | | |
| SEMA4B | -0.40 | -0.46 | | |
| AC006028.3 | -0.38 | -0.48 | | |
| SH3BP2 | -0.38 | -0.51 | | |
| KIF7 | -0.38 | -0.43 | | |
| FAM59B | -0.38 | -0.45 | | |
| GPR125 | -0.38 | -0.43 | | |
| SMTN | -0.37 | -0.53 | | |
| PDE9A | -0.37 | -0.50 | | |
| FADS2 | -0.37 | -0.42 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001614 | purinergic nucleotide receptor activity | IDA | | 8834001 |
| GO:0004872 | receptor activity | IEA | | - |
| GO:0004931 | ATP-gated cation channel activity | TAS | | 9565569 |
| GO:0005524 | ATP binding | IEA | | - |
| GO:0005262 | calcium channel activity | EXP | | 2457808 |
| GO:0042803 | protein homodimerization activity | NAS | | 17895406 |
| GO:0046982 | protein heterodimerization activity | NAS | | 17895406 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007165 | signal transduction | TAS | | 9565569 |
| GO:0006811 | ion transport | IDA | | 8834001 |
| GO:0006940 | regulation of smooth muscle contraction | IEA | | - |
| GO:0006915 | apoptosis | IEA | | - |
| GO:0007320 | insemination | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0005886 | plasma membrane | EXP | | 2457808 |
| GO:0005887 | integral to plasma membrane | TAS | | 9565569 |
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