Gene Page: TRAT1

Summary
GeneID  50852
Symbol  TRAT1
Synonyms  HSPC062|TCRIM|TRIM
Description  T cell receptor associated transmembrane adaptor 1
See related  HGNC:30698|MIM:604962|Ensembl:ENSG00000163519|HPRD:05392|
Locus tag  -
Gene type  protein-coding
Map location  3q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04359 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.04047 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005068transmembrane receptor protein tyrosine kinase adaptor protein activityTAS9687533 
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activityEXP12660731 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001920negative regulation of receptor recyclingIDA11390434 
GO:0006968cellular defense responseTAS9687533 
GO:0007165signal transductionTAS9687533 
GO:0006955immune responseIEA-
GO:0051051negative regulation of transportIDA11390434 
GO:0050862positive regulation of T cell receptor signaling pathwayIDA11390434 
GO:0050850positive regulation of calcium-mediated signalingIDA11390434 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042101T cell receptor complexIDASynap (GO term level: 8)11390434 
GO:0005886plasma membraneEXP12660731 
GO:0005886plasma membraneIDA11390434 
GO:0005887integral to plasma membraneTAS9687533 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD247CD3-ZETA | CD3H | CD3Q | CD3Z | T3Z | TCRZCD247 molecule-HPRD9687533 |11390434 
-HPRD,BioGRID11390434 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YESReconstituted ComplexBioGRID10790433 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Reconstituted ComplexBioGRID10790433 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinaseReconstituted ComplexBioGRID10790433 
LCP2SLP-76 | SLP76lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)Reconstituted ComplexBioGRID10790433 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homologReconstituted ComplexBioGRID10790433 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD10723796 
TRA@FLJ22602 | MGC117436 | MGC22624 | MGC23964 | MGC71411 | TCRA | TCRD | TRAT cell receptor alpha locus-HPRD11390434 
 


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