Gene Page

Gene Page: SH3GLB1

Summary

GeneID

51100

Symbol

SH3GLB1

Synonyms

Bif-1|CGI-61|KIAA0491|dJ612B15.2

Description

SH3-domain GRB2-like endophilin B1

Locus tag

Gene type

protein-coding

Map location

1p22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.1263

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

11161816

GO:0008289

lipid binding

IEA

GO:0042803

protein homodimerization activity

IPI

11161816

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006916

anti-apoptosis

IDA

11161816

GO:0006915

apoptosis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000139

Golgi membrane

IEA

GO:0005794

Golgi apparatus

IEA

GO:0005737

cytoplasm

IDA

11161816

GO:0005739

mitochondrion

IEA

GO:0005741

mitochondrial outer membrane

IEA

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ADAM9	KIAA0021 \| MCMP \| MDC9 \| Mltng	ADAM metallopeptidase domain 9 (meltrin gamma)	-	HPRD	10531379
AMPH	AMPH1	amphiphysin	-	HPRD,BioGRID	12456676
ARHGAP17	DKFZp564A1363 \| FLJ37567 \| FLJ43368 \| MGC87805 \| MST066 \| MST110 \| MSTP038 \| MSTP066 \| MSTP110 \| NADRIN \| RICH1 \| WBP15	Rho GTPase activating protein 17	Reconstituted Complex	BioGRID	11431473
BAX	BCL2L4	BCL2-associated X protein	An unspecified isoform of Bax interacts with SH3GLB1.	BIND	11161816
BAX	BCL2L4	BCL2-associated X protein	-	HPRD,BioGRID	11161816 \|11259440
BIN1	AMPH2 \| AMPHL \| DKFZp547F068 \| MGC10367 \| SH3P9	bridging integrator 1	-	HPRD,BioGRID	12456676
DNM1	DNM	dynamin 1	Reconstituted Complex	BioGRID	12456676
DNM2	CMTDI1 \| CMTDIB \| DI-CMTB \| DYN2 \| DYNII	dynamin 2	-	HPRD	12456676
HTT	HD \| IT15	huntingtin	-	HPRD,BioGRID	12456676
SH3GLB1	Bif-1 \| CGI-61 \| KIAA0491 \| dJ612B15.2	SH3-domain GRB2-like endophilin B1	SH3GLB1 forms a homodimer.	BIND	11161816
SH3GLB2	KIAA1848 \| PP6569 \| PP9455	SH3-domain GRB2-like endophilin B2	SH3GLB1 interacts with SH3GLB2.	BIND	11161816
SH3GLB2	KIAA1848 \| PP6569 \| PP9455	SH3-domain GRB2-like endophilin B2	-	HPRD,BioGRID	11161816
SH3KBP1	CIN85 \| GIG10 \| MIG18	SH3-domain kinase binding protein 1	Reconstituted Complex	BioGRID	11894096
SYNJ1	INPP5G	synaptojanin 1	-	HPRD	14704270

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-142-3p	595	601	m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-181	3939	3945	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-29	2794	2801	1A,m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-30-3p	103	110	1A,m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	103	110	1A,m8	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-382	267	273	1A	hsa-miR-382^brain	GAAGUUGUUCGUGGUGGAUUCG
miR-410	42	48	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-9	387	393	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.