Gene Page

Gene Page: REV1

Summary

GeneID

51455

Symbol

REV1

Synonyms

FLJ21523|MGC163283|MGC26225|REV1L

Description

REV1 homolog (S. cerevisiae)

Locus tag

Gene type

protein-coding

Map location

2q11.1-q11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0004

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000287

magnesium ion binding

IEA

GO:0003684

damaged DNA binding

TAS

10536157

GO:0005515

protein binding

IPI

11485998

GO:0016740

transferase activity

IEA

GO:0017125

deoxycytidyl transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006281

DNA repair

IEA

GO:0006260

DNA replication

TAS

10536157

GO:0009411

response to UV

IDA

11485998

GO:0042276

error-prone postreplication DNA repair

TAS

11485998

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
FHL2	AAG11 \| DRAL \| SLIM3	four and a half LIM domains 2	-	HPRD	10906324
MAD2L2	MAD2B \| REV7	MAD2 mitotic arrest deficient-like 2 (yeast)	-	HPRD	11485998 \|12529368 \|15189446
MAD2L2	MAD2B \| REV7	MAD2 mitotic arrest deficient-like 2 (yeast)	REV1 interacts with REV7.	BIND	11485998
POLH	FLJ16395 \| FLJ21978 \| RAD30 \| RAD30A \| XP-V \| XPV	polymerase (DNA directed), eta	hREV1 interacts with POLH.	BIND	15189446
POLH	FLJ16395 \| FLJ21978 \| RAD30 \| RAD30A \| XP-V \| XPV	polymerase (DNA directed), eta	-	HPRD	15189446
POLI	RAD30B \| RAD3OB	polymerase (DNA directed) iota	hREV1 interacts with POLI.	BIND	15189446
POLI	RAD30B \| RAD3OB	polymerase (DNA directed) iota	-	HPRD	15189446
POLK	DINB1 \| DINP \| POLQ	polymerase (DNA directed) kappa	hREV1 interacts with POLK.	BIND	15189446
POLK	DINB1 \| DINP \| POLQ	polymerase (DNA directed) kappa	-	HPRD	15189446
POLL	BETA-N \| FLJ46002 \| POL-KAPPA	polymerase (DNA directed), lambda	-	HPRD	14657033
REV3L	POLZ \| REV3	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	-	HPRD	15189446

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-182	147	153	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-200bc/429	159	165	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-203.1	129	135	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-30-5p	259	266	1A,m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-486	298	304	m8	hsa-miR-486	UCCUGUACUGAGCUGCCCCGAG
miR-495	222	228	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-496	167	174	1A,m8	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-96	146	153	1A,m8	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.