Gene Page

Gene Page: HDAC7

Summary

GeneID

51564

Symbol

HDAC7

Synonyms

DKFZp586J0917|FLJ99588|HD7A|HDAC7A

Description

histone deacetylase 7

Locus tag

Gene type

protein-coding

Map location

12q13.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004407

histone deacetylase activity

TAS

12711221

GO:0016787

hydrolase activity

IEA

GO:0008134

transcription factor binding

TAS

12711221

GO:0016566

specific transcriptional repressor activity

TAS

12711221

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007399

nervous system development

TAS

neurite (GO term level: 5)

12711221

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

GO:0006954

inflammatory response

TAS

12711221

GO:0016568

chromatin modification

TAS

12711221

GO:0030183

B cell differentiation

TAS

12711221

GO:0045843

negative regulation of striated muscle development

TAS

12711221

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000118

histone deacetylase complex

TAS

12711221

GO:0005634

nucleus

TAS

12711221

GO:0005737

cytoplasm

TAS

12711221

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
BCL6	BCL5 \| BCL6A \| LAZ3 \| ZBTB27 \| ZNF51	B-cell CLL/lymphoma 6	Affinity Capture-Western Reconstituted Complex	BioGRID	11929873
EDNRA	ETA \| ETRA	endothelin receptor type A	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	11262386
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	Affinity Capture-Western Reconstituted Complex	BioGRID	11466315
IKZF1	Hs.54452 \| IK1 \| IKAROS \| LYF1 \| PRO0758 \| ZNFN1A1 \| hIk-1	IKAROS family zinc finger 1 (Ikaros)	Affinity Capture-Western	BioGRID	12015313
IKZF3	AIO \| AIOLOS \| ZNFN1A3	IKAROS family zinc finger 3 (Aiolos)	Affinity Capture-Western	BioGRID	12015313
IKZF4	EOS \| KIAA1782 \| ZNFN1A4	IKAROS family zinc finger 4 (Eos)	Affinity Capture-Western	BioGRID	12015313
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K(lysine) acetyltransferase 5	Affinity Capture-Western Two-hybrid	BioGRID	12551922
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	nuclear receptor co-repressor 1	Affinity Capture-Western Reconstituted Complex	BioGRID	11466315
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	Affinity Capture-Western	BioGRID	11466315
PPARD	FAAR \| MGC3931 \| NR1C2 \| NUC1 \| NUCI \| NUCII \| PPAR-beta \| PPARB	peroxisome proliferator-activated receptor delta	PPAR-delta interacts with HDAC7. This interaction was modelled on a demonstrated interaction between PPAR-delta and HDAC7 from unspecified sources.	BIND	12970571
SFN	YWHAS	stratifin	Affinity Capture-MS	BioGRID	15778465
ZBTB16	PLZF \| ZNF145	zinc finger and BTB domain containing 16	Reconstituted Complex	BioGRID	11929873

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-150	856	862	1A	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.