Gene Page: PECAM1

Summary
GeneID  5175
Symbol  PECAM1
Synonyms  CD31|PECAM-1
Description  platelet/endothelial cell adhesion molecule
See related  HGNC:8823|MIM:173445|Ensembl:ENSG00000198802|HPRD:01425|
Locus tag  -
Gene type  protein-coding
Map location  17q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0402 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TNRC6A0.640.61
WDR270.640.64
ZNF5280.640.58
CDRT40.630.60
QRICH20.630.64
ZNF4180.630.63
NINL0.630.68
C19orf440.630.63
FAM18B20.620.60
POLE0.620.66
Top 10 negatively co-expressed genes
AF347015.31-0.46-0.56
AF347015.27-0.44-0.54
IFI27-0.44-0.51
MT-CO2-0.43-0.53
B2M-0.43-0.49
MT-CYB-0.43-0.53
ABCG2-0.42-0.44
C5orf53-0.42-0.46
AF347015.33-0.41-0.50
TNFSF12-0.41-0.41
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10801826 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
GO:0007165signal transductionTAS7994021 
GO:0008037cell recognitionTAS1690453 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005615extracellular spaceIDA9290466 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneEXP8080982 |9054388 |9774457 
|10350061 |10858437 
GO:0005886plasma membraneTAS1690453 
GO:0031092platelet alpha granule membraneEXP8080982 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD38T10CD38 molecule-HPRD9551996 
CSKMGC117393c-src tyrosine kinase-HPRD,BioGRID9624175 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDa-HPRD,BioGRID10801826 
DSPDPI | DPIIdesmoplakin-HPRD,BioGRID10801826 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID10858437 
HCKJTK9hemopoietic cell kinase-HPRD,BioGRID10858437 
INPP5DMGC104855 | MGC142140 | MGC142142 | SHIP | SHIP1 | SIP-145 | hp51CNinositol polyphosphate-5-phosphatase, 145kDaFar Western
Reconstituted Complex
BioGRID10350061 
ITGA5CD49e | FNRA | VLA5Aintegrin, alpha 5 (fibronectin receptor, alpha polypeptide)-HPRD10982404 
ITGB3CD61 | GP3A | GPIIIaintegrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Co-localizationBioGRID10982404 
JUPARVD12 | CTNNG | DP3 | DPIII | PDGB | PKGBjunction plakoglobinAffinity Capture-WesternBioGRID10801826 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD,BioGRID9624175 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homolog-HPRD,BioGRID10858437 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1Affinity Capture-WesternBioGRID10801826 
PECAM1CD31 | PECAM-1platelet/endothelial cell adhesion moleculeReconstituted ComplexBioGRID10425179 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)Affinity Capture-WesternBioGRID9774384 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1-HPRD,BioGRID10350061 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11Affinity Capture-Western
Far Western
Reconstituted Complex
BioGRID9054388 |9774457 
|10350061 |10801826 
PTPN6HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1protein tyrosine phosphatase, non-receptor type 6-HPRD,BioGRID9774457 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)-HPRD,BioGRID10858437 
XRCC6CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAAX-ray repair complementing defective repair in Chinese hamster cells 6Two-hybridBioGRID16169070 
YES1HsT441 | P61-YES | Yes | c-yesv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1-HPRD,BioGRID10858437 
 


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