Gene Page: PFKM

Summary
GeneID  5213
Symbol  PFKM
Synonyms  GSD7|MGC8699|PFK-1|PFK-M|PFKX
Description  phosphofructokinase, muscle
See related  HGNC:8877|MIM:610681|Ensembl:ENSG00000152556|HPRD:01988|
Locus tag  -
Gene type  protein-coding
Map location  12q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PSMD40.840.83
TUFM0.810.82
TXN20.800.81
PSMB50.800.81
HBXIP0.800.82
AC063943.40.800.81
PSMA70.800.77
COPS60.790.79
UBB0.790.87
PRELID10.790.85
Top 10 negatively co-expressed genes
AF347015.33-0.49-0.50
AF347015.8-0.48-0.45
AF347015.26-0.47-0.47
AF347015.18-0.47-0.47
APOL1-0.47-0.52
MT-CYB-0.46-0.47
MT-CO2-0.46-0.42
AF347015.2-0.46-0.45
MT-ATP8-0.46-0.49
AF347015.21-0.45-0.42
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:00038726-phosphofructokinase activityIDA6444721 
GO:00038726-phosphofructokinase activityIEA-
GO:00038726-phosphofructokinase activityNAS-
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:0008022protein C-terminus bindingIPI12649290 
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006110regulation of glycolysisTAS8444874 
GO:0006096glycolysisIEA-
GO:0006096glycolysisNAS-
GO:0005977glycogen metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP6444721 
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIDA18029348 
GO:00059456-phosphofructokinase complexIDA6444721 
GO:00059456-phosphofructokinase complexIEA-
GO:00059456-phosphofructokinase complexNAS-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATP6V0A4A4 | ATP6N1B | ATP6N2 | MGC130016 | MGC130017 | RDRTA2 | RTA1C | RTADR | STV1 | VPH1 | VPP2ATPase, H+ transporting, lysosomal V0 subunit a4-HPRD,BioGRID12649290 
CAV3LGMD1C | LQT9 | MGC126100 | MGC126101 | MGC126129 | VIP-21 | VIP21caveolin 3-HPRD,BioGRID9252390 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1-HPRD14760703 
FHL2AAG11 | DRAL | SLIM3four and a half LIM domains 2Reconstituted ComplexBioGRID12432079 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-128390396m8hsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-3202922981Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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