Gene Page

Gene Page: POU4F1

Summary

GeneID

5457

Symbol

POU4F1

Synonyms

BRN3A|FLJ13449|Oct-T1|RDC-1

Description

POU class 4 homeobox 1

Locus tag

Gene type

protein-coding

Map location

13q31.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 5

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

TAS

8995448

GO:0005515

protein binding

IEA

GO:0043565

sequence-specific DNA binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007416

synaptogenesis

TAS

Synap (GO term level: 6)

8995448

GO:0007409

axonogenesis

TAS

neuron, axon, neurite (GO term level: 12)

8995448

GO:0021953

central nervous system neuron differentiation

IEA

neuron (GO term level: 9)

GO:0048934

peripheral nervous system neuron differentiation

IEA

neuron (GO term level: 9)

GO:0021535

cell migration in hindbrain

IEA

Brain (GO term level: 9)

GO:0001967

suckling behavior

IEA

GO:0006357

regulation of transcription from RNA polymerase II promoter

TAS

8995448

GO:0007275

multicellular organismal development

IEA

GO:0043065

positive regulation of apoptosis

IEA

GO:0051355

proprioception during equilibrioception

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	Reconstituted Complex Two-hybrid	BioGRID	9448000
EWSR1	EWS	Ewing sarcoma breakpoint region 1	-	HPRD,BioGRID	12432261
RIT2	RIBA \| RIN \| ROC2	Ras-like without CAAX 2	-	HPRD,BioGRID	12934100

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-130/301	1492	1499	1A,m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-133	398	405	1A,m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	398	405	1A,m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-141/200a	2048	2054	m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	2048	2054	m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-153	1853	1859	m8	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-19	1491	1497	m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	1491	1497	m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-30-3p	2229	2235	m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
				hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
				hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
				hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-326	372	378	1A	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-34/449	2043	2049	1A	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-34b	1931	1937	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-376c	410	416	1A	hsa-miR-376c	AACAUAGAGGAAAUUCCACG
miR-493-5p	412	419	1A,m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.