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|
| GeneID |
5498
|
| Symbol |
PPOX
|
| Synonyms |
MGC8485|PPO|V290M|VP
|
| Description |
protoporphyrinogen oxidase |
| See related |
HGNC:9280|MIM:600923|Ensembl:ENSG00000143224|HPRD:02953| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
1q22 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00814 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| ATP2B1 | 0.89 | 0.88 | | |
| RNF6 | 0.87 | 0.84 | | |
| ARHGEF9 | 0.86 | 0.90 | | |
| ITPR1 | 0.86 | 0.79 | | |
| PPP1R16B | 0.86 | 0.80 | | |
| LANCL1 | 0.86 | 0.87 | | |
| PDE8B | 0.86 | 0.83 | | |
| PLCB1 | 0.85 | 0.90 | | |
| FAM179B | 0.85 | 0.85 | | |
| DGKB | 0.84 | 0.67 | | |
Top 10 negatively co-expressed genes | | BCL7C | -0.48 | -0.54 | | |
| DBI | -0.45 | -0.53 | | |
| EFEMP2 | -0.44 | -0.51 | | |
| RAB34 | -0.43 | -0.52 | | |
| RHOC | -0.40 | -0.51 | | |
| NUDT8 | -0.40 | -0.46 | | |
| IRF7 | -0.40 | -0.54 | | |
| AC006276.2 | -0.39 | -0.39 | | |
| C1orf61 | -0.39 | -0.52 | | |
| HEBP2 | -0.39 | -0.48 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004729 | protoporphyrinogen oxidase activity | EXP | | 8771201 |
| GO:0004729 | protoporphyrinogen oxidase activity | IDA | | 7713909 |
| GO:0009055 | electron carrier activity | IEA | | - |
| GO:0016491 | oxidoreductase activity | IEA | | - |
| GO:0050660 | FAD binding | TAS | | 7713909 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006783 | heme biosynthetic process | IDA | | 7713909 |
| GO:0055114 | oxidation reduction | IDA | | 7713909 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005739 | mitochondrion | IEA | | - |
| GO:0005758 | mitochondrial intermembrane space | EXP | | 8771201 |
| GO:0016020 | membrane | IEA | | - |
| GO:0031304 | intrinsic to mitochondrial inner membrane | ISS | | - |
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