Gene Page: SMPD4

Summary
GeneID  55627
Symbol  SMPD4
Synonyms  FLJ20297|FLJ20756|KIAA1418|NSMASE3|nSMase-3
Description  sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
See related  HGNC:32949|MIM:610457|Ensembl:ENSG00000136699|HPRD:13374|
Locus tag  -
Gene type  protein-coding
Map location  2q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000287magnesium ion bindingIEA-
GO:0005515protein bindingIPI15231747 
GO:0004767sphingomyelin phosphodiesterase activityIEA-
GO:0016787hydrolase activityIEA-
GO:0050290sphingomyelin phosphodiesterase D activityIDA16517606 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006685sphingomyelin catabolic processIDA16517606 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIDA16517606 
GO:0005802trans-Golgi networkIDA16517606 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIDA16517606 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRF2BRFU | FLJ11052 | TFIIIB50BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-likeAffinity Capture-MSBioGRID17353931 
EXOSC4FLJ20591 | RRP41 | RRP41A | Rrp41p | SKI6 | Ski6p | hRrp41p | p12Aexosome component 4-HPRD15231747 
 


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