Gene Page: SFRS3

Summary
GeneID  6428
Symbol  SFRS3
Synonyms  SRp20
Description  splicing factor, arginine/serine-rich 3
See related  HGNC:10785|MIM:603364|Ensembl:ENSG00000112081|HPRD:04530|
Locus tag  -
Gene type  protein-coding
Map location  6p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PLOD10.720.70
GRN0.720.73
STAT30.700.71
IVD0.660.68
TMEM2140.660.67
SLC41A10.650.70
SIDT20.650.66
TRIM80.630.60
SUOX0.630.63
DPAGT10.620.58
Top 10 negatively co-expressed genes
FAM159B-0.44-0.50
AC087071.1-0.39-0.27
AL050337.1-0.39-0.26
SYCP3-0.39-0.29
SPDYA-0.38-0.35
RP9P-0.38-0.39
C8orf59-0.36-0.35
NOX1-0.36-0.32
AC011475.1-0.36-0.36
DDTL-0.35-0.26
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingTAS2030943 
GO:0005515protein bindingIPI15169763 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000398nuclear mRNA splicing, via spliceosomeEXP12226669 
GO:0008380RNA splicingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHD1DKFZp686E2337chromodomain helicase DNA binding protein 1-HPRD,BioGRID12890497 
CLK1CLK | CLK/STY | STYCDC-like kinase 1Two-hybridBioGRID12890497 
EXOSC6EAP4 | MTR3 | Mtr3p | hMtr3p | p11exosome component 6-HPRD,BioGRID15231747 
HNRNPKCSBP | FLJ41122 | HNRPK | TUNPheterogeneous nuclear ribonucleoprotein KSRp20 interacts with hnRNP K. This interaction was modeled on a demonstrated interaction between hnRNP K from an unspecified source and human SRp20.BIND10809782 
RBM7FLJ11153RNA binding motif protein 7-HPRD,BioGRID12634307 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD,BioGRID10757789 |11991645 
|14559993 
-HPRD11991645 
SFRS2IPCASP11 | SIP1 | SRRP129splicing factor, arginine/serine-rich 2, interacting protein-HPRD,BioGRID9447963 
SIP1GEMIN2 | SIP1-deltasurvival of motor neuron protein interacting protein 1-HPRD9447963 
SRPK1SFRSK1SFRS protein kinase 1-HPRD8208298 |10390541 
SRPK2FLJ36101 | SFRSK2SFRS protein kinase 2Biochemical ActivityBioGRID9472028 
YWHAQ14-3-3 | 1C5 | HS1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptideAffinity Capture-MSBioGRID17353931 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/206858864m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-218995m8hsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-33143214381Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-378*845851m8hsa-miR-422bCUGGACUUGGAGUCAGAAGGCC
hsa-miR-422aCUGGACUUAGGGUCAGAAGGCC
miR-409-3p857863m8hsa-miR-409-3pCGAAUGUUGCUCGGUGAACCCCU
miR-433-3p12991305m8hsa-miR-433brainAUCAUGAUGGGCUCCUCGGUGU
miR-48625321A,m8hsa-miR-486UCCUGUACUGAGCUGCCCCGAG
miR-493-5p5561m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-496130513111Ahsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.