Gene Page: PACS1

Summary
GeneID  55690
Symbol  PACS1
Synonyms  FLJ10209|KIAA1175
Description  phosphofurin acidic cluster sorting protein 1
See related  HGNC:30032|MIM:607492|Ensembl:ENSG00000175115|HPRD:06320|
Locus tag  -
Gene type  protein-coding
Map location  11q13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0067 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCA40.660.46
KCNJ130.650.39
SLC13A40.650.40
C1S0.650.67
CP0.640.48
SLC5A50.640.46
SLC2A120.630.59
CLIC60.620.44
C2orf400.620.34
F50.620.46
Top 10 negatively co-expressed genes
SH2B2-0.36-0.48
CHD3-0.34-0.40
SOX12-0.34-0.41
AKAP8L-0.33-0.41
PABPN1-0.33-0.39
ANO8-0.33-0.39
XKR7-0.33-0.37
DPF1-0.33-0.39
ZNF250-0.33-0.37
AP006289.1-0.33-0.36
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10707087 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000042protein targeting to GolgiIEA-
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005829cytosolEXP15569716 
GO:0030137COPI-coated vesicleIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CLCN7CLC-7 | CLC7 | FLJ26686 | FLJ39644 | FLJ46423 | OPTA2 | OPTB4chloride channel 7PACS-1 interacts with CLC-7.BIND15692563 
FURINFUR | PACE | PCSK3 | SPC1furin (paired basic amino acid cleaving enzyme)-HPRD,BioGRID9695949 |11331585 
IGF2RCD222 | CIMPR | M6P-R | MPR1 | MPRIinsulin-like growth factor 2 receptor-HPRD9695949 |11331585 
JUNAP-1 | AP1 | c-Junjun oncogene-HPRD11331585 
PKD2APKD2 | MGC138466 | MGC138468 | PC2 | PKD4polycystic kidney disease 2 (autosomal dominant)PACS-1 interacts with PKD2.BIND15692563 
TRPV4OTRPC4 | TRP12 | VR-OAC | VRL-2 | VRL2 | VROACtransient receptor potential cation channel, subfamily V, member 4PACS-1 interacts with an unspecified isoform of TRPV4.BIND15692563 
VAMP4VAMP24vesicle-associated membrane protein 4-HPRD,BioGRID14608369 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-34/4491421491A,m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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