Gene Page: PRKCG

Summary
GeneID  5582
Symbol  PRKCG
Synonyms  MGC57564|PKC-gamma|PKCC|PKCG|SCA14
Description  protein kinase C, gamma
See related  HGNC:9402|MIM:176980|Ensembl:ENSG00000126583|HPRD:01502|
Locus tag  -
Gene type  protein-coding
Map location  19q13.4
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.08 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004697protein kinase C activityTAS3755548 
GO:0005509calcium ion bindingIEA-
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0019992diacylglycerol bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationTAS3755548 
GO:0008219cell deathIEA-
GO:0007242intracellular signaling cascadeIEA-
GO:0007635chemosensory behaviorIEA-
GO:0042177negative regulation of protein catabolic processIDA15808853 
GO:0031397negative regulation of protein ubiquitinationIDA15808853 
GO:0032425positive regulation of mismatch repairIDA15808853 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030425dendriteIEAneuron, axon, dendrite (GO term level: 6)-
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AFAP1AFAP | AFAP-110 | FLJ56849actin filament associated protein 1-HPRD,BioGRID12134071 
GABRA1ECA4 | EJMgamma-aminobutyric acid (GABA) A receptor, alpha 1-HPRD,BioGRID12091471 
GABRA4-gamma-aminobutyric acid (GABA) A receptor, alpha 4Affinity Capture-WesternBioGRID12091471 
GRIA4GLUR4 | GLUR4C | GLURDglutamate receptor, ionotrophic, AMPA 4-HPRD,BioGRID12471040 
GRIN1NMDA1 | NMDAR1 | NR1glutamate receptor, ionotropic, N-methyl D-aspartate 1-HPRD10862698 
HABP4IHABP4 | Ki-1/57 | MGC825 | SERBP1Lhyaluronan binding protein 4-HPRD14699138 
PDLIM5ENH | ENH1 | L9 | LIMPDZ and LIM domain 5-HPRD8940095 
PPP1R14ACPI-17 | CPI17 | PPP1INLprotein phosphatase 1, regulatory (inhibitor) subunit 14A-HPRD15003508 
RGS2G0S8regulator of G-protein signaling 2, 24kDa-HPRD,BioGRID11063746 
TIAM1FLJ36302T-cell lymphoma invasion and metastasis 1-HPRD,BioGRID10212259 
YWHAG14-3-3GAMMAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide-HPRD,BioGRID10433554 
 


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