Gene Page: CBWD1
Summary ?
| GeneID | 55871 |
| Symbol | CBWD1 |
| Synonyms | COBP |
| Description | COBW domain containing 1 |
| Reference | MIM:611078|HGNC:HGNC:17134|Ensembl:ENSG00000172785|HPRD:16686|Vega:OTTHUMG00000019425 |
| Gene type | protein-coding |
| Map location | 9p24.3 |
| Pascal p-value | 2.707E-4 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellum Cortex Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs823066 | chr1 | 205771172 | CBWD1 | 55871 | 0.02 | trans | ||
| rs11120206 | chr1 | 206610593 | CBWD1 | 55871 | 0.1 | trans | ||
| rs2716734 | chr2 | 39947720 | CBWD1 | 55871 | 0.02 | trans | ||
| rs2716736 | chr2 | 39947946 | CBWD1 | 55871 | 0.02 | trans | ||
| rs2003180 | chr3 | 87169338 | CBWD1 | 55871 | 0.09 | trans | ||
| rs16869878 | chr5 | 2523760 | CBWD1 | 55871 | 0.06 | trans | ||
| rs467856 | chr5 | 3128168 | CBWD1 | 55871 | 0.03 | trans | ||
| snp_a-2169623 | 0 | CBWD1 | 55871 | 0.13 | trans | |||
| rs13175086 | chr5 | 174691428 | CBWD1 | 55871 | 8.045E-4 | trans | ||
| rs2016128 | chr6 | 42442743 | CBWD1 | 55871 | 0.09 | trans | ||
| rs4947631 | chr7 | 50603378 | CBWD1 | 55871 | 0.02 | trans | ||
| rs10124277 | chr9 | 8499294 | CBWD1 | 55871 | 0.18 | trans | ||
| rs7298298 | chr12 | 17810638 | CBWD1 | 55871 | 0.09 | trans | ||
| rs9890514 | chr17 | 46738882 | CBWD1 | 55871 | 0.14 | trans | ||
| rs225434 | chr21 | 43724740 | CBWD1 | 55871 | 0.11 | trans | ||
| rs523348 | 9 | 202004 | CBWD1 | ENSG00000172785.14 | 1.562E-6 | 0 | -13025 | gtex_brain_ba24 |
| rs56265100 | 9 | 203481 | CBWD1 | ENSG00000172785.14 | 6.069E-7 | 0 | -14502 | gtex_brain_ba24 |
| rs626629 | 9 | 203802 | CBWD1 | ENSG00000172785.14 | 6.019E-7 | 0 | -14823 | gtex_brain_ba24 |
| rs141716985 | 9 | 203898 | CBWD1 | ENSG00000172785.14 | 1.521E-6 | 0 | -14919 | gtex_brain_ba24 |
| rs573452 | 9 | 203937 | CBWD1 | ENSG00000172785.14 | 5.777E-7 | 0 | -14958 | gtex_brain_ba24 |
| rs573246 | 9 | 204014 | CBWD1 | ENSG00000172785.14 | 1.376E-6 | 0 | -15035 | gtex_brain_ba24 |
| rs551317 | 9 | 204060 | CBWD1 | ENSG00000172785.14 | 5.64E-7 | 0 | -15081 | gtex_brain_ba24 |
| rs625358 | 9 | 204082 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -15103 | gtex_brain_ba24 |
| rs613181 | 9 | 204485 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -15506 | gtex_brain_ba24 |
| rs612287 | 9 | 204694 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -15715 | gtex_brain_ba24 |
| rs483582 | 9 | 205452 | CBWD1 | ENSG00000172785.14 | 2.729E-8 | 0 | -16473 | gtex_brain_ba24 |
| rs533567 | 9 | 207454 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -18475 | gtex_brain_ba24 |
| rs530776 | 9 | 207755 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -18776 | gtex_brain_ba24 |
| rs528912 | 9 | 207958 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -18979 | gtex_brain_ba24 |
| rs644809 | 9 | 208549 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -19570 | gtex_brain_ba24 |
| rs631411 | 9 | 209325 | CBWD1 | ENSG00000172785.14 | 5.917E-7 | 0 | -20346 | gtex_brain_ba24 |
| rs488787 | 9 | 212908 | CBWD1 | ENSG00000172785.14 | 1.173E-6 | 0 | -23929 | gtex_brain_ba24 |
| rs636922 | 9 | 215269 | CBWD1 | ENSG00000172785.14 | 8.72E-8 | 0 | -26290 | gtex_brain_ba24 |
| rs2484966 | 9 | 216493 | CBWD1 | ENSG00000172785.14 | 2.278E-6 | 0 | -27514 | gtex_brain_ba24 |
| rs627889 | 9 | 216707 | CBWD1 | ENSG00000172785.14 | 1.032E-6 | 0 | -27728 | gtex_brain_ba24 |
| rs529045 | 9 | 217397 | CBWD1 | ENSG00000172785.14 | 2.288E-6 | 0 | -28418 | gtex_brain_ba24 |
| rs500785 | 9 | 218183 | CBWD1 | ENSG00000172785.14 | 1.069E-7 | 0 | -29204 | gtex_brain_ba24 |
| rs578062 | 9 | 219449 | CBWD1 | ENSG00000172785.14 | 1.43E-7 | 0 | -30470 | gtex_brain_ba24 |
| rs2479319 | 9 | 219528 | CBWD1 | ENSG00000172785.14 | 1.16E-6 | 0 | -30549 | gtex_brain_ba24 |
| rs575307 | 9 | 219774 | CBWD1 | ENSG00000172785.14 | 1.159E-6 | 0 | -30795 | gtex_brain_ba24 |
| rs574399 | 9 | 219875 | CBWD1 | ENSG00000172785.14 | 1.158E-6 | 0 | -30896 | gtex_brain_ba24 |
| rs663013 | 9 | 220070 | CBWD1 | ENSG00000172785.14 | 1.243E-6 | 0 | -31091 | gtex_brain_ba24 |
| rs489140 | 9 | 222272 | CBWD1 | ENSG00000172785.14 | 1.056E-6 | 0 | -33293 | gtex_brain_ba24 |
| rs617467 | 9 | 223332 | CBWD1 | ENSG00000172785.14 | 2.523E-7 | 0 | -34353 | gtex_brain_ba24 |
| rs541645 | 9 | 224227 | CBWD1 | ENSG00000172785.14 | 4.252E-7 | 0 | -35248 | gtex_brain_ba24 |
| rs2484968 | 9 | 226157 | CBWD1 | ENSG00000172785.14 | 1.699E-7 | 0 | -37178 | gtex_brain_ba24 |
| rs519184 | 9 | 227615 | CBWD1 | ENSG00000172785.14 | 4.063E-7 | 0 | -38636 | gtex_brain_ba24 |
| rs624098 | 9 | 229283 | CBWD1 | ENSG00000172785.14 | 4.762E-7 | 0 | -40304 | gtex_brain_ba24 |
| rs546727 | 9 | 234907 | CBWD1 | ENSG00000172785.14 | 4.277E-7 | 0 | -45928 | gtex_brain_ba24 |
| rs589269 | 9 | 240578 | CBWD1 | ENSG00000172785.14 | 1.101E-6 | 0 | -51599 | gtex_brain_ba24 |
| rs500931 | 9 | 244284 | CBWD1 | ENSG00000172785.14 | 8.22E-7 | 0 | -55305 | gtex_brain_ba24 |
| rs660877 | 9 | 244577 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -55598 | gtex_brain_ba24 |
| rs140406776 | 9 | 248531 | CBWD1 | ENSG00000172785.14 | 2.294E-6 | 0 | -59552 | gtex_brain_ba24 |
| rs785838 | 9 | 248749 | CBWD1 | ENSG00000172785.14 | 2.36E-6 | 0 | -59770 | gtex_brain_ba24 |
| rs785842 | 9 | 249992 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -61013 | gtex_brain_ba24 |
| rs680567 | 9 | 250609 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -61630 | gtex_brain_ba24 |
| rs679542 | 9 | 250889 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -61910 | gtex_brain_ba24 |
| rs491805 | 9 | 251244 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -62265 | gtex_brain_ba24 |
| rs648745 | 9 | 251726 | CBWD1 | ENSG00000172785.14 | 9.844E-7 | 0 | -62747 | gtex_brain_ba24 |
| rs554921 | 9 | 269534 | CBWD1 | ENSG00000172785.14 | 1.025E-6 | 0 | -80555 | gtex_brain_ba24 |
| rs532701 | 9 | 272270 | CBWD1 | ENSG00000172785.14 | 1.561E-7 | 0 | -83291 | gtex_brain_ba24 |
| rs785847 | 9 | 272325 | CBWD1 | ENSG00000172785.14 | 9.357E-8 | 0 | -83346 | gtex_brain_ba24 |
| rs41321045 | 9 | 150524 | CBWD1 | ENSG00000172785.14 | 2.433E-6 | 0 | 38455 | gtex_brain_putamen_basal |
| rs2992842 | 9 | 156135 | CBWD1 | ENSG00000172785.14 | 1.272E-9 | 0 | 32844 | gtex_brain_putamen_basal |
| rs2998958 | 9 | 170391 | CBWD1 | ENSG00000172785.14 | 1.129E-6 | 0 | 18588 | gtex_brain_putamen_basal |
| rs76769706 | 9 | 172941 | CBWD1 | ENSG00000172785.14 | 9.733E-7 | 0 | 16038 | gtex_brain_putamen_basal |
| rs2785386 | 9 | 174634 | CBWD1 | ENSG00000172785.14 | 1.539E-6 | 0 | 14345 | gtex_brain_putamen_basal |
| rs1932752 | 9 | 185653 | CBWD1 | ENSG00000172785.14 | 1.692E-6 | 0 | 3326 | gtex_brain_putamen_basal |
| rs1932753 | 9 | 185662 | CBWD1 | ENSG00000172785.14 | 2.422E-8 | 0 | 3317 | gtex_brain_putamen_basal |
| rs3008110 | 9 | 186603 | CBWD1 | ENSG00000172785.14 | 1.849E-6 | 0 | 2376 | gtex_brain_putamen_basal |
| rs4025476 | 9 | 193438 | CBWD1 | ENSG00000172785.14 | 9.484E-7 | 0 | -4459 | gtex_brain_putamen_basal |
| rs3008143 | 9 | 193737 | CBWD1 | ENSG00000172785.14 | 1.037E-7 | 0 | -4758 | gtex_brain_putamen_basal |
| rs2992873 | 9 | 198364 | CBWD1 | ENSG00000172785.14 | 3.848E-8 | 0 | -9385 | gtex_brain_putamen_basal |
| rs3008163 | 9 | 198571 | CBWD1 | ENSG00000172785.14 | 2.873E-7 | 0 | -9592 | gtex_brain_putamen_basal |
| rs523348 | 9 | 202004 | CBWD1 | ENSG00000172785.14 | 1.483E-7 | 0 | -13025 | gtex_brain_putamen_basal |
| rs643058 | 9 | 202399 | CBWD1 | ENSG00000172785.14 | 1.676E-6 | 0 | -13420 | gtex_brain_putamen_basal |
| rs629280 | 9 | 203226 | CBWD1 | ENSG00000172785.14 | 1.731E-7 | 0 | -14247 | gtex_brain_putamen_basal |
| rs56265100 | 9 | 203481 | CBWD1 | ENSG00000172785.14 | 1.11E-7 | 0 | -14502 | gtex_brain_putamen_basal |
| rs626629 | 9 | 203802 | CBWD1 | ENSG00000172785.14 | 1.388E-7 | 0 | -14823 | gtex_brain_putamen_basal |
| rs141716985 | 9 | 203898 | CBWD1 | ENSG00000172785.14 | 4.288E-9 | 0 | -14919 | gtex_brain_putamen_basal |
| rs149525865 | 9 | 203899 | CBWD1 | ENSG00000172785.14 | 1.505E-9 | 0 | -14920 | gtex_brain_putamen_basal |
| rs573452 | 9 | 203937 | CBWD1 | ENSG00000172785.14 | 1.403E-7 | 0 | -14958 | gtex_brain_putamen_basal |
| rs573246 | 9 | 204014 | CBWD1 | ENSG00000172785.14 | 4.29E-9 | 0 | -15035 | gtex_brain_putamen_basal |
| rs551317 | 9 | 204060 | CBWD1 | ENSG00000172785.14 | 1.367E-7 | 0 | -15081 | gtex_brain_putamen_basal |
| rs625358 | 9 | 204082 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -15103 | gtex_brain_putamen_basal |
| rs613181 | 9 | 204485 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -15506 | gtex_brain_putamen_basal |
| rs612287 | 9 | 204694 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -15715 | gtex_brain_putamen_basal |
| rs483582 | 9 | 205452 | CBWD1 | ENSG00000172785.14 | 1.086E-7 | 0 | -16473 | gtex_brain_putamen_basal |
| rs581731 | 9 | 206838 | CBWD1 | ENSG00000172785.14 | 9.338E-7 | 0 | -17859 | gtex_brain_putamen_basal |
| rs533567 | 9 | 207454 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -18475 | gtex_brain_putamen_basal |
| rs530776 | 9 | 207755 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -18776 | gtex_brain_putamen_basal |
| rs528912 | 9 | 207958 | CBWD1 | ENSG00000172785.14 | 1.392E-7 | 0 | -18979 | gtex_brain_putamen_basal |
| rs644809 | 9 | 208549 | CBWD1 | ENSG00000172785.14 | 1.105E-7 | 0 | -19570 | gtex_brain_putamen_basal |
| rs644383 | 9 | 208665 | CBWD1 | ENSG00000172785.14 | 8.851E-8 | 0 | -19686 | gtex_brain_putamen_basal |
| rs631411 | 9 | 209325 | CBWD1 | ENSG00000172785.14 | 2.161E-7 | 0 | -20346 | gtex_brain_putamen_basal |
| rs522747 | 9 | 211472 | CBWD1 | ENSG00000172785.14 | 1.152E-7 | 0 | -22493 | gtex_brain_putamen_basal |
| rs520015 | 9 | 211762 | CBWD1 | ENSG00000172785.14 | 8.821E-8 | 0 | -22783 | gtex_brain_putamen_basal |
| rs488787 | 9 | 212908 | CBWD1 | ENSG00000172785.14 | 1.039E-7 | 0 | -23929 | gtex_brain_putamen_basal |
| rs636922 | 9 | 215269 | CBWD1 | ENSG00000172785.14 | 3.949E-8 | 0 | -26290 | gtex_brain_putamen_basal |
| rs635615 | 9 | 215534 | CBWD1 | ENSG00000172785.14 | 8.476E-7 | 0 | -26555 | gtex_brain_putamen_basal |
| rs2479318 | 9 | 215917 | CBWD1 | ENSG00000172785.14 | 4.82E-7 | 0 | -26938 | gtex_brain_putamen_basal |
| rs627889 | 9 | 216707 | CBWD1 | ENSG00000172785.14 | 1.234E-7 | 0 | -27728 | gtex_brain_putamen_basal |
| rs500785 | 9 | 218183 | CBWD1 | ENSG00000172785.14 | 6.119E-8 | 0 | -29204 | gtex_brain_putamen_basal |
| rs578062 | 9 | 219449 | CBWD1 | ENSG00000172785.14 | 4.489E-8 | 0 | -30470 | gtex_brain_putamen_basal |
| rs663013 | 9 | 220070 | CBWD1 | ENSG00000172785.14 | 1.244E-7 | 0 | -31091 | gtex_brain_putamen_basal |
| rs489140 | 9 | 222272 | CBWD1 | ENSG00000172785.14 | 1.174E-7 | 0 | -33293 | gtex_brain_putamen_basal |
| rs617467 | 9 | 223332 | CBWD1 | ENSG00000172785.14 | 7.477E-7 | 0 | -34353 | gtex_brain_putamen_basal |
| rs541645 | 9 | 224227 | CBWD1 | ENSG00000172785.14 | 4.759E-7 | 0 | -35248 | gtex_brain_putamen_basal |
| rs589627 | 9 | 224976 | CBWD1 | ENSG00000172785.14 | 8.469E-9 | 0 | -35997 | gtex_brain_putamen_basal |
| rs199545790 | 9 | 225167 | CBWD1 | ENSG00000172785.14 | 1.984E-6 | 0 | -36188 | gtex_brain_putamen_basal |
| rs78827914 | 9 | 225168 | CBWD1 | ENSG00000172785.14 | 5.918E-7 | 0 | -36189 | gtex_brain_putamen_basal |
| rs519184 | 9 | 227615 | CBWD1 | ENSG00000172785.14 | 4.682E-7 | 0 | -38636 | gtex_brain_putamen_basal |
| rs624098 | 9 | 229283 | CBWD1 | ENSG00000172785.14 | 6.714E-7 | 0 | -40304 | gtex_brain_putamen_basal |
| rs589269 | 9 | 240578 | CBWD1 | ENSG00000172785.14 | 1.554E-6 | 0 | -51599 | gtex_brain_putamen_basal |
| rs500931 | 9 | 244284 | CBWD1 | ENSG00000172785.14 | 1.582E-6 | 0 | -55305 | gtex_brain_putamen_basal |
| rs660877 | 9 | 244577 | CBWD1 | ENSG00000172785.14 | 1.582E-6 | 0 | -55598 | gtex_brain_putamen_basal |
| rs643800 | 9 | 261190 | CBWD1 | ENSG00000172785.14 | 1.088E-6 | 0 | -72211 | gtex_brain_putamen_basal |
| rs554921 | 9 | 269534 | CBWD1 | ENSG00000172785.14 | 2.651E-7 | 0 | -80555 | gtex_brain_putamen_basal |
| rs532701 | 9 | 272270 | CBWD1 | ENSG00000172785.14 | 2.551E-6 | 0 | -83291 | gtex_brain_putamen_basal |
| rs785847 | 9 | 272325 | CBWD1 | ENSG00000172785.14 | 1.596E-6 | 0 | -83346 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BASAKI YBX1 TARGETS UP | 290 | 177 | All SZGR 2.0 genes in this pathway |
| BENPORATH MYC MAX TARGETS | 775 | 494 | All SZGR 2.0 genes in this pathway |
| SHEPARD BMYB MORPHOLINO UP | 205 | 126 | All SZGR 2.0 genes in this pathway |
| SANSOM APC TARGETS | 212 | 121 | All SZGR 2.0 genes in this pathway |
| GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 2 DN | 336 | 211 | All SZGR 2.0 genes in this pathway |