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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MAPK9

Summary

GeneID

5601

Symbol

MAPK9

Synonyms

Description

mitogen-activated protein kinase 9

Locus tag

Gene type

protein-coding

Map location

5q35

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.0276

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0004707

MAP kinase activity

IEA

GO:0004705

JUN kinase activity

IDA

8654373

GO:0005515

protein binding

IPI

15158451

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

GO:0007254

JNK cascade

IDA

8654373

GO:0006950

response to stress

TAS

7969172

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACP5	MGC117378 \| TRAP	acid phosphatase 5, tartrate resistant	Two-hybrid	BioGRID	16169070
ATF2	CRE-BP1 \| CREB2 \| HB16 \| MGC111558 \| TREB7	activating transcription factor 2	An unspecified isoform of JNK2 interacts with and phosphorylates ATF2.	BIND	9155018
ATF7	ATFA \| MGC57182	activating transcription factor 7	-	HPRD,BioGRID	8649858
DUSP1	CL100 \| HVH1 \| MKP-1 \| MKP1 \| PTPN10	dual specificity phosphatase 1	Affinity Capture-Western	BioGRID	11359773
DUSP10	MKP-5 \| MKP5	dual specificity phosphatase 10	Affinity Capture-Western	BioGRID	11359773
DUSP16	KIAA1700 \| MGC129701 \| MGC129702 \| MKP-7 \| MKP7	dual specificity phosphatase 16	-	HPRD,BioGRID	11359773
DUSP19	DUSP17 \| LMWDSP3 \| MGC138210 \| SKRP1 \| TS-DSP1	dual specificity phosphatase 19	-	HPRD,BioGRID	11959861
ELK1	-	ELK1, member of ETS oncogene family	An unspecified isoform of JNK2 interacts with and phosphorylates Elk-1.	BIND	9155018
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	Reconstituted Complex	BioGRID	7642542 \|9019171
HSF1	HSTF1	heat shock transcription factor 1	-	HPRD,BioGRID	11527157
IRS1	HIRS-1	insulin receptor substrate 1	-	HPRD	12417588
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	JNK2beta2 interacts with c-Jun.	BIND	12167088
			JNK2alpha2 interacts with c-Jun.	BIND	12167088
			Biochemical Activity	BioGRID	8945519
			JNK2beta1 interacts with c-Jun.	BIND	12167088
			JNK2alpha1 interacts with c-Jun.	BIND	12167088
			An unspecified isoform of JNK2 interacts with and phosphorylates c-Jun.	BIND	9155018
JUNB	AP-1	jun B proto-oncogene	Reconstituted Complex	BioGRID	8945519
JUND	AP-1	jun D proto-oncogene	-	HPRD	8945519
KIAA1377	-	KIAA1377	Two-hybrid	BioGRID	16169070
KIAA1712	PS1TP3	KIAA1712	Two-hybrid	BioGRID	16189514
MAPK8IP1	IB1 \| JIP-1 \| JIP1 \| PRKM8IP	mitogen-activated protein kinase 8 interacting protein 1	Affinity Capture-Western Reconstituted Complex	BioGRID	9733513 \|10490659
MAPK8IP2	IB2 \| JIP2 \| PRKM8IPL	mitogen-activated protein kinase 8 interacting protein 2	Affinity Capture-Western Reconstituted Complex	BioGRID	10490659
MAPK8IP3	DKFZp762N1113 \| FLJ00027 \| JIP3 \| JSAP1 \| KIAA1066 \| SYD2	mitogen-activated protein kinase 8 interacting protein 3	-	HPRD,BioGRID	10523642 \|10629060 \|12189133
MAPKAPK5	PRAK	mitogen-activated protein kinase-activated protein kinase 5	-	HPRD	9628874
PRKD1	PKC-MU \| PKCM \| PKD \| PRKCM	protein kinase D1	Affinity Capture-Western	BioGRID	11948398
PRKDC	DNA-PKcs \| DNAPK \| DNPK1 \| HYRC \| HYRC1 \| XRCC7 \| p350	protein kinase, DNA-activated, catalytic polypeptide	Biochemical Activity	BioGRID	11749722
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	Rb interacts with JNK2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and JNK2 from an unspecified species.	BIND	11566021
SF3B4	MGC10828 \| SAP49 \| SF3b49	splicing factor 3b, subunit 4, 49kDa	Two-hybrid	BioGRID	16189514
SH3BP5	SAB	SH3-domain binding protein 5 (BTK-associated)	-	HPRD,BioGRID	12167088
			Sab interacts with JNK2-alpha-2.	BIND	12167088
			Sab interacts with JNK2-alpha-1.	BIND	12167088
			Sab interacts with JNK2-beta-2.	BIND	12167088
			Sab interacts with JNK2-beta-1.	BIND	12167088
TOB1	APRO6 \| MGC104792 \| MGC34446 \| PIG49 \| TOB \| TROB \| TROB1	transducer of ERBB2, 1	Affinity Capture-Western Biochemical Activity Reconstituted Complex	BioGRID	12151396
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	9393873
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	-	HPRD	10490605
WDR62	C19orf14 \| DKFZp434J046 \| DKFZp686G1024 \| FLJ33298 \| MGC166976	WD repeat domain 62	Two-hybrid	BioGRID	16189514
XPNPEP1	SAMP \| XPNPEP \| XPNPEPL \| XPNPEPL1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	Two-hybrid	BioGRID	16169070
XPO7	KIAA0745 \| RANBP16	exportin 7	Two-hybrid	BioGRID	16169070
ZBTB25	KUP \| ZNF46	zinc finger and BTB domain containing 25	Two-hybrid	BioGRID	16189514

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-17-5p/20/93.mr/106/519.d	361	367	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	385	391	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-203.1	233	239	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-205	30	36	1A	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-496	105	111	m8	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-93.hd/291-3p/294/295/302/372/373/520	360	366	m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU
miR-96	385	391	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.