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| GeneID |
5689
|
| Symbol |
PSMB1
|
| Synonyms |
FLJ25321|HC5|KIAA1838|PMSB1|PSC5
|
| Description |
proteasome (prosome, macropain) subunit, beta type, 1 |
| See related |
HGNC:9537|MIM:602017|Ensembl:ENSG00000008018|HPRD:03603| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
6q27 |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0443 | |
|
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| General Gene Expression (microarray) ? |
|
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| |
| Gene Expression in Brain Regions (new) |
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| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| DBI | 0.72 | 0.71 | | |
| IMMP1L | 0.71 | 0.68 | | |
| MTHFS | 0.70 | 0.64 | | |
| MTCP1NB | 0.70 | 0.67 | | |
| CD63 | 0.68 | 0.63 | | |
| PSME1 | 0.67 | 0.60 | | |
| PTPMT1 | 0.67 | 0.61 | | |
| FTHL16 | 0.66 | 0.61 | | |
| RHOC | 0.66 | 0.59 | | |
| ST20 | 0.66 | 0.61 | | |
Top 10 negatively co-expressed genes | | A2BP1 | -0.56 | -0.58 | | |
| DNM3 | -0.56 | -0.60 | | |
| CLCN4 | -0.55 | -0.58 | | |
| FAM123A | -0.55 | -0.59 | | |
| HERC3 | -0.54 | -0.55 | | |
| NFASC | -0.53 | -0.57 | | |
| CNNM2 | -0.53 | -0.56 | | |
| C1orf96 | -0.52 | -0.51 | | |
| SLCO3A1 | -0.52 | -0.54 | | |
| PLCL1 | -0.52 | -0.58 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005515 | protein binding | IPI | | 15231747 |17353931 |
| GO:0004298 | threonine-type endopeptidase activity | IEA | | - |
| GO:0008233 | peptidase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | | - |
| GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | EXP | | 11285280 |
| GO:0051436 | negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle | EXP | | 15029244 |
| GO:0051437 | positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | EXP | | 12791267 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005829 | cytosol | IEA | | - |
| GO:0005839 | proteasome core complex | IEA | | - |
| GO:0005634 | nucleus | IEA | | - |
| GO:0005737 | cytoplasm | IEA | | - |
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