Gene Page: PSME2

Summary
GeneID  5721
Symbol  PSME2
Synonyms  PA28B|PA28beta|REGbeta
Description  proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
See related  HGNC:9569|MIM:602161|Ensembl:ENSG00000100911|HPRD:03697|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LENG80.790.72
PLA2G4B0.760.72
TNFRSF250.760.70
CPT1B0.750.70
ZNF6920.750.68
PILRB0.740.72
LAT0.740.66
MYO15B0.740.72
EXD30.730.61
CSAD0.730.72
Top 10 negatively co-expressed genes
ITM2A-0.40-0.41
ELTD1-0.39-0.35
CHPT1-0.33-0.35
TM4SF18-0.32-0.30
ABCG2-0.32-0.31
GLO1-0.31-0.32
LYRM5-0.31-0.35
SNX3-0.31-0.32
DNAJB9-0.31-0.33
PRCP-0.31-0.29
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008538proteasome activator activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processEXP11285280 
GO:0051436negative regulation of ubiquitin-protein ligase activity during mitotic cell cycleEXP15029244 
GO:0051437positive regulation of ubiquitin-protein ligase activity during mitotic cell cycleEXP12791267 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000502proteasome complexTAS8811196 
GO:0005829cytosolIEA-
GO:0008537proteasome activator complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PSME1IFI5111 | MGC8628 | PA28A | PA28alpha | REGalphaproteasome (prosome, macropain) activator subunit 1 (PA28 alpha)-HPRD,BioGRID8663520 
PSME2PA28B | PA28beta | REGbetaproteasome (prosome, macropain) activator subunit 2 (PA28 beta)Two-hybridBioGRID16189514 
 


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