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| GeneID |
5746
|
| Symbol |
PTH2R
|
| Synonyms |
PTHR2
|
| Description |
parathyroid hormone 2 receptor |
| See related |
HGNC:9609|MIM:601469|Ensembl:ENSG00000144407|HPRD:03276| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
2q33 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00916 | | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01016 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.009 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| AC005512.1 | 0.91 | 0.21 | | |
| RGS14 | 0.91 | 0.15 | | |
| ADORA2A | 0.91 | 0.23 | | |
| TMEM90A | 0.89 | 0.26 | | |
| RASD2 | 0.89 | 0.21 | | |
| WNT6 | 0.88 | 0.23 | | |
| AP003108.2 | 0.88 | 0.14 | | |
| DDIT4L | 0.87 | 0.26 | | |
| ANKRD34B | 0.86 | 0.14 | | |
| SH3RF2 | 0.86 | 0.31 | | |
Top 10 negatively co-expressed genes | | MEIS3P2 | -0.24 | -0.14 | | |
| BLVRA | -0.20 | -0.25 | | |
| GNAS | -0.18 | -0.05 | | |
| FXYD6 | -0.18 | -0.19 | | |
| LRFN2 | -0.18 | -0.16 | | |
| SH2D3C | -0.17 | -0.08 | | |
| TUBA1B | -0.17 | -0.17 | | |
| AC106818.2 | -0.17 | -0.17 | | |
| RTN4RL2 | -0.17 | -0.14 | | |
| DYRK3 | -0.17 | -0.18 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004872 | receptor activity | IEA | | - |
| GO:0004930 | G-protein coupled receptor activity | IEA | | - |
| GO:0004991 | parathyroid hormone receptor activity | TAS | | 7797535 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0002062 | chondrocyte differentiation | IEA | | - |
| GO:0002076 | osteoblast development | IEA | | - |
| GO:0007200 | G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | IEA | | - |
| GO:0007189 | G-protein signaling, adenylate cyclase activating pathway | IEA | | - |
| GO:0007165 | signal transduction | IEA | | - |
| GO:0008284 | positive regulation of cell proliferation | IEA | | - |
| GO:0008285 | negative regulation of cell proliferation | IEA | | - |
| GO:0048469 | cell maturation | IEA | | - |
| GO:0006874 | cellular calcium ion homeostasis | IEA | | - |
| GO:0030282 | bone mineralization | IEA | | - |
| GO:0045453 | bone resorption | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 7797535 |
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