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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CGN

Summary

GeneID

57530

Symbol

CGN

Synonyms

DKFZp779N1112|FLJ39281|KIAA1319

Description

cingulin

Locus tag

Gene type

protein-coding

Map location

1q21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003779

actin binding

ISS

GO:0003774

motor activity

IEA

GO:0005515

protein binding

IPI

11042084

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008150

biological_process

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005923

tight junction

NAS

Brain (GO term level: 10)

12529927

GO:0016459

myosin complex

IEA

GO:0030054

cell junction

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARHGEF2	DKFZp547L106 \| DKFZp547P1516 \| GEF \| GEF-H1 \| GEFH1 \| KIAA0651 \| LFP40 \| P40	rho/rac guanine nucleotide exchange factor (GEF) 2	ARHGEF2 (GEF-H1) interacts with CGN (Cingulin). This interaction was modeled on a demonstrated interaction between canine GEF-H1 and canine and human Cingulin.	BIND	15866167
SFN	YWHAS	stratifin	Affinity Capture-MS	BioGRID	15778465
TJP1	DKFZp686M05161 \| MGC133289 \| ZO-1	tight junction protein 1 (zona occludens 1)	-	HPRD,BioGRID	10613913 \|12023291\|11042084
			-	HPRD	11042084
			Cingulin interacts with ZO-1.	BIND	10613913
TJP2	MGC26306 \| X104 \| ZO-2 \| ZO2	tight junction protein 2 (zona occludens 2)	-	HPRD,BioGRID	11042084
TJP2	MGC26306 \| X104 \| ZO-2 \| ZO2	tight junction protein 2 (zona occludens 2)	-	HPRD	10613913 \|12023291\|11042084
YWHAB	GW128 \| HS1 \| KCIP-1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	Affinity Capture-MS	BioGRID	17353931
YWHAG	14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	-	HPRD	15324660
YWHAG	14-3-3GAMMA		Affinity Capture-MS	BioGRID	17353931

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	601	607	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	600	607	1A,m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	600	607	1A,m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-125/351	366	373	1A,m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	366	373	1A,m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-185	664	670	1A	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-186	342	349	1A,m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-188	309	316	1A,m8	hsa-miR-188	CAUCCCUUGCAUGGUGGAGGGU
miR-19	490	497	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	490	497	1A,m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-320	336	342	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-409-3p	654	660	1A	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.