Gene Page: WDFY4
Summary ?
| GeneID | 57705 |
| Symbol | WDFY4 |
| Synonyms | C10orf64 |
| Description | WDFY family member 4 |
| Reference | MIM:613316|HGNC:HGNC:29323|Ensembl:ENSG00000128815| |
| Gene type | protein-coding |
| Map location | 10q11.23 |
| Pascal p-value | 0.02 |
| Fetal beta | -1.489 |
| eGene | Frontal Cortex BA9 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| UBE2C | 0.99 | 0.72 |
| AURKB | 0.98 | 0.72 |
| TACC3 | 0.98 | 0.73 |
| GTSE1 | 0.98 | 0.79 |
| KIF20A | 0.98 | 0.72 |
| PLK1 | 0.98 | 0.77 |
| HJURP | 0.97 | 0.74 |
| MYBL2 | 0.97 | 0.72 |
| AC087645.2 | 0.97 | 0.74 |
| KIFC1 | 0.97 | 0.78 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-F | -0.38 | -0.68 |
| C5orf53 | -0.38 | -0.61 |
| PTH1R | -0.38 | -0.63 |
| FBXO2 | -0.37 | -0.55 |
| SLC9A3R2 | -0.37 | -0.42 |
| AF347015.27 | -0.36 | -0.73 |
| TINAGL1 | -0.36 | -0.64 |
| AIFM3 | -0.36 | -0.60 |
| ALDOC | -0.36 | -0.58 |
| AF347015.31 | -0.36 | -0.70 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP | 579 | 346 | All SZGR 2.0 genes in this pathway |
| PASQUALUCCI LYMPHOMA BY GC STAGE DN | 165 | 104 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS EARLY PROGENITOR | 532 | 309 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |