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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PTPRN

Summary

GeneID

5798

Symbol

PTPRN

Synonyms

FLJ16131|IA-2|IA-2/PTP|IA2|ICA512|R-PTP-N

Description

protein tyrosine phosphatase, receptor type, N

Locus tag

Gene type

protein-coding

Map location

2q35-q36.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01016

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00916

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MBD1

0.93

0.94

IP6K1

0.93

EARS2

0.91

BAHD1

0.91

0.93

DHX30

0.91

0.90

CEP68

0.91

0.93

ZFYVE1

0.91

0.90

BSDC1

0.91

0.90

NOL6

0.91

CSNK1D

0.91

0.90

Top 10 negatively co-expressed genes

AF347015.21

-0.79

-0.83

AF347015.31

-0.77

MT-CO2

-0.76

AF347015.8

-0.75

-0.76

AF347015.33

-0.73

MT-CYB

-0.73

FXYD1

-0.73

-0.74

AF347015.27

-0.72

-0.75

AC021016.1

-0.71

-0.73

HIGD1B

-0.71

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005001

transmembrane receptor protein tyrosine phosphatase activity

TAS

8024693

GO:0004872

receptor activity

IEA

GO:0005515

protein binding

IPI

11043403 |16273344

GO:0016791

phosphatase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006470

protein amino acid dephosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

GO:0005887

integral to plasma membrane

TAS

8024693

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CAPN2	CANP2 \| CANPL2 \| CANPml \| FLJ39928 \| mCANP	calpain 2, (m/II) large subunit	Biochemical Activity	BioGRID	11483505
NOS1	IHPS1 \| NOS \| nNOS	nitric oxide synthase 1 (neuronal)	-	HPRD	11043403
SNTB2	D16S2531E \| EST25263 \| SNT2B2 \| SNT3 \| SNTL	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	-	HPRD,BioGRID	11483505
SPTBN4	KIAA1642 \| QV \| SPNB4 \| SPTBN3	spectrin, beta, non-erythrocytic 4	-	HPRD,BioGRID	11086001

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-203.1	536	542	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-342	50	56	m8	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC
miR-377	49	55	m8	hsa-miR-377	AUCACACAAAGGCAACUUUUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.