Gene Page: RHOU

Summary
GeneID  58480
Symbol  RHOU
Synonyms  ARHU|CDC42L1|DJ646B12.2|FLJ10616|WRCH1|fJ646B12.2|hG28K
Description  ras homolog gene family, member U
See related  HGNC:17794|MIM:606366|Ensembl:ENSG00000116574|HPRD:06965|
Locus tag  -
Gene type  protein-coding
Map location  1q42.11-q42.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MPG0.800.73
CCDC240.800.82
SCO20.800.79
SLC2A110.790.74
AUP10.780.78
PUSL10.780.77
MRPL550.770.76
DGCR6L0.770.70
MRPL40.770.72
TMEM2230.770.70
Top 10 negatively co-expressed genes
MT-ATP8-0.38-0.37
ZNHIT6-0.38-0.37
SEC62-0.36-0.47
AF347015.18-0.35-0.35
CCDC55-0.34-0.29
AF347015.26-0.33-0.32
KIF5B-0.33-0.28
AF347015.8-0.32-0.29
MYO6-0.32-0.33
MYH9-0.32-0.23
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:0003924GTPase activityIEA-
GO:0005515protein bindingIPI15350535 |18086875 
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000082G1/S transition of mitotic cell cycleIEA-
GO:0008360regulation of cell shapeIEA-
GO:0016601Rac protein signal transductionIEA-
GO:0007264small GTPase mediated signal transductionIEA-
GO:0030036actin cytoskeleton organizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005622intracellularIEA-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Wrch-1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between human Wrch-1 and Grb2 from an unspecified species.BIND15556869 
NCK1MGC12668 | NCK | NCKalphaNCK adaptor protein 1Wrch-1 interacts with Nck. This interaction was modeled on a demonstrated interaction between human Wrch-1, and Nck from an unspecified species.BIND15556869 
PAK1MGC130000 | MGC130001 | PAKalphap21 protein (Cdc42/Rac)-activated kinase 1Wrch-1 interacts with PAK. This interaction was modeled on a demonstrated interactions between human Wrch-1 and rat PAK.BIND15556869 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1Wrch-1 interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human Wrch-1 and PLC-gamma from an unspecified species.BIND15556869 
 


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